Middle Ear Packing and External Ear Packing With Fibrin Glue Enhance the Success of Fat Myringoplasty Without Hyaluronic Acid Disc
Recently, hyaluronic acid disc has been known to enhance the success rate of fat myringoplasty. However, hyaluronic acid disc (Epidisc) is not covered by south Korean medical insurance. To date, fat myringoplasty using middle ear packing has rarely been reported. In this study, we studied whether mi...
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Veröffentlicht in: | In vivo (Athens) 2022-01, Vol.36 (1), p.490-495 |
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creator | Kim, Jongmin Park, Hyung-Joo Lee, Dae-Neung Jang, Chul Ho |
description | Recently, hyaluronic acid disc has been known to enhance the success rate of fat myringoplasty. However, hyaluronic acid disc (Epidisc) is not covered by south Korean medical insurance. To date, fat myringoplasty using middle ear packing has rarely been reported. In this study, we studied whether middle ear packing with dexamethasone soaked gelfoam and fibrin glue over the fat graft could promote the success rate of tympanic membrane perforation (TMP) closure without hyaluronic acid disc, regardless of perforation size.
Between January 2005 and July 2020, a total of 209 patients who underwent fat myringoplasty due to chronic TMP at a tertiary referral center were enrolled, and the success rate and audiologic outcomes were analyzed.
The mean successful tympanic membrane (TM) closure rate was 88.0%. The success rate by different age groups showed no significant difference. Further, the size of perforation showed no significant difference, and the perforation site (anterior or posterior) was not significant. The preoperative mean thresholds of air conduction (AC), bone conduction (BC), and air-bone gap (ABG) were 55.71, 12.98, and 42.73 dB respectively. The postoperative mean thresholds of AC, BC, and ABG were 23.67, 12.98, and 10.69 dB, respectively. Change in preoperative and postoperative hearing showed was statistically significant.
Middle ear packing by gelfoam combined with external ear canal packing using fibrin glue enabled stable adhesion between the remnant TM and the fat graft. Regardless of the size of the TMP, the success rate of the fat myringoplasty by our technique can be enhanced without use of hyaluronic acid disc. |
doi_str_mv | 10.21873/invivo.12729 |
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Between January 2005 and July 2020, a total of 209 patients who underwent fat myringoplasty due to chronic TMP at a tertiary referral center were enrolled, and the success rate and audiologic outcomes were analyzed.
The mean successful tympanic membrane (TM) closure rate was 88.0%. The success rate by different age groups showed no significant difference. Further, the size of perforation showed no significant difference, and the perforation site (anterior or posterior) was not significant. The preoperative mean thresholds of air conduction (AC), bone conduction (BC), and air-bone gap (ABG) were 55.71, 12.98, and 42.73 dB respectively. The postoperative mean thresholds of AC, BC, and ABG were 23.67, 12.98, and 10.69 dB, respectively. Change in preoperative and postoperative hearing showed was statistically significant.
Middle ear packing by gelfoam combined with external ear canal packing using fibrin glue enabled stable adhesion between the remnant TM and the fat graft. Regardless of the size of the TMP, the success rate of the fat myringoplasty by our technique can be enhanced without use of hyaluronic acid disc.</description><identifier>ISSN: 0258-851X</identifier><identifier>EISSN: 1791-7549</identifier><identifier>DOI: 10.21873/invivo.12729</identifier><identifier>PMID: 34972753</identifier><language>eng</language><publisher>Greece: International Institute of Anticancer Research</publisher><subject>Ear, Middle ; Fibrin Tissue Adhesive ; Humans ; Hyaluronic Acid ; Myringoplasty ; Retrospective Studies ; Treatment Outcome ; Tympanic Membrane ; Tympanic Membrane Perforation - surgery</subject><ispartof>In vivo (Athens), 2022-01, Vol.36 (1), p.490-495</ispartof><rights>Copyright © 2022 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.</rights><rights>Copyright 2022, International Institute of Anticancer Research 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765178/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765178/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34972753$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Jongmin</creatorcontrib><creatorcontrib>Park, Hyung-Joo</creatorcontrib><creatorcontrib>Lee, Dae-Neung</creatorcontrib><creatorcontrib>Jang, Chul Ho</creatorcontrib><title>Middle Ear Packing and External Ear Packing With Fibrin Glue Enhance the Success of Fat Myringoplasty Without Hyaluronic Acid Disc</title><title>In vivo (Athens)</title><addtitle>In Vivo</addtitle><description>Recently, hyaluronic acid disc has been known to enhance the success rate of fat myringoplasty. However, hyaluronic acid disc (Epidisc) is not covered by south Korean medical insurance. To date, fat myringoplasty using middle ear packing has rarely been reported. In this study, we studied whether middle ear packing with dexamethasone soaked gelfoam and fibrin glue over the fat graft could promote the success rate of tympanic membrane perforation (TMP) closure without hyaluronic acid disc, regardless of perforation size.
Between January 2005 and July 2020, a total of 209 patients who underwent fat myringoplasty due to chronic TMP at a tertiary referral center were enrolled, and the success rate and audiologic outcomes were analyzed.
The mean successful tympanic membrane (TM) closure rate was 88.0%. The success rate by different age groups showed no significant difference. Further, the size of perforation showed no significant difference, and the perforation site (anterior or posterior) was not significant. The preoperative mean thresholds of air conduction (AC), bone conduction (BC), and air-bone gap (ABG) were 55.71, 12.98, and 42.73 dB respectively. The postoperative mean thresholds of AC, BC, and ABG were 23.67, 12.98, and 10.69 dB, respectively. Change in preoperative and postoperative hearing showed was statistically significant.
Middle ear packing by gelfoam combined with external ear canal packing using fibrin glue enabled stable adhesion between the remnant TM and the fat graft. Regardless of the size of the TMP, the success rate of the fat myringoplasty by our technique can be enhanced without use of hyaluronic acid disc.</description><subject>Ear, Middle</subject><subject>Fibrin Tissue Adhesive</subject><subject>Humans</subject><subject>Hyaluronic Acid</subject><subject>Myringoplasty</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><subject>Tympanic Membrane</subject><subject>Tympanic Membrane Perforation - surgery</subject><issn>0258-851X</issn><issn>1791-7549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkUtvEzEURi0EoqGwZIu8ZDOpH-OxZ1OpKklbqRVIgGBnefxIDI6d2p6IbPnljJJStau7uOf77pUOAO8xmhMsOD3zced3aY4JJ_0LMMO8xw1nbf8SzBBhohEM_zwBb0r5hVDHESKvwQlte044ozPw984bEyxcqAy_KP3bxxVU0cDFn2pzVOHZ4oeva7j0Q_YRXoVxSsW1itrCurbw66i1LQUmB5eqwrv9RK3SNqhS94dkGiu83qsw5hS9hhfaG_jJF_0WvHIqFPvuYZ6C78vFt8vr5vbz1c3lxW2jaUtrIwyiHW0dJ23vTMcJUa1wZuiQQoK02g2WMdcKyxVmiFI-UN0bq2wnOHeDoafg_Ni7HYeNNdrGmlWQ2-w3Ku9lUl4-30S_lqu0k4J3DHMxFXx8KMjpfrSlys30vg1BRZvGIkmHWT9J6dmENkdU51RKtu7xDEby4E0evcmDt4n_8PS3R_q_KPoPakGXVQ</recordid><startdate>20220101</startdate><enddate>20220101</enddate><creator>Kim, Jongmin</creator><creator>Park, Hyung-Joo</creator><creator>Lee, Dae-Neung</creator><creator>Jang, Chul Ho</creator><general>International Institute of Anticancer Research</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220101</creationdate><title>Middle Ear Packing and External Ear Packing With Fibrin Glue Enhance the Success of Fat Myringoplasty Without Hyaluronic Acid Disc</title><author>Kim, Jongmin ; Park, Hyung-Joo ; Lee, Dae-Neung ; Jang, Chul Ho</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c343t-8d03634f7249fd6722a48fdb60a0824cfbe55f48e7a150337b3c9deae6877fbd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Ear, Middle</topic><topic>Fibrin Tissue Adhesive</topic><topic>Humans</topic><topic>Hyaluronic Acid</topic><topic>Myringoplasty</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><topic>Tympanic Membrane</topic><topic>Tympanic Membrane Perforation - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Jongmin</creatorcontrib><creatorcontrib>Park, Hyung-Joo</creatorcontrib><creatorcontrib>Lee, Dae-Neung</creatorcontrib><creatorcontrib>Jang, Chul Ho</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>In vivo (Athens)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Jongmin</au><au>Park, Hyung-Joo</au><au>Lee, Dae-Neung</au><au>Jang, Chul Ho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Middle Ear Packing and External Ear Packing With Fibrin Glue Enhance the Success of Fat Myringoplasty Without Hyaluronic Acid Disc</atitle><jtitle>In vivo (Athens)</jtitle><addtitle>In Vivo</addtitle><date>2022-01-01</date><risdate>2022</risdate><volume>36</volume><issue>1</issue><spage>490</spage><epage>495</epage><pages>490-495</pages><issn>0258-851X</issn><eissn>1791-7549</eissn><abstract>Recently, hyaluronic acid disc has been known to enhance the success rate of fat myringoplasty. However, hyaluronic acid disc (Epidisc) is not covered by south Korean medical insurance. To date, fat myringoplasty using middle ear packing has rarely been reported. In this study, we studied whether middle ear packing with dexamethasone soaked gelfoam and fibrin glue over the fat graft could promote the success rate of tympanic membrane perforation (TMP) closure without hyaluronic acid disc, regardless of perforation size.
Between January 2005 and July 2020, a total of 209 patients who underwent fat myringoplasty due to chronic TMP at a tertiary referral center were enrolled, and the success rate and audiologic outcomes were analyzed.
The mean successful tympanic membrane (TM) closure rate was 88.0%. The success rate by different age groups showed no significant difference. Further, the size of perforation showed no significant difference, and the perforation site (anterior or posterior) was not significant. The preoperative mean thresholds of air conduction (AC), bone conduction (BC), and air-bone gap (ABG) were 55.71, 12.98, and 42.73 dB respectively. The postoperative mean thresholds of AC, BC, and ABG were 23.67, 12.98, and 10.69 dB, respectively. Change in preoperative and postoperative hearing showed was statistically significant.
Middle ear packing by gelfoam combined with external ear canal packing using fibrin glue enabled stable adhesion between the remnant TM and the fat graft. Regardless of the size of the TMP, the success rate of the fat myringoplasty by our technique can be enhanced without use of hyaluronic acid disc.</abstract><cop>Greece</cop><pub>International Institute of Anticancer Research</pub><pmid>34972753</pmid><doi>10.21873/invivo.12729</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Ear, Middle Fibrin Tissue Adhesive Humans Hyaluronic Acid Myringoplasty Retrospective Studies Treatment Outcome Tympanic Membrane Tympanic Membrane Perforation - surgery |
title | Middle Ear Packing and External Ear Packing With Fibrin Glue Enhance the Success of Fat Myringoplasty Without Hyaluronic Acid Disc |
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