Chemoproteomic Approach toward Probing the Interactomes of Perfluoroalkyl Substances

Poly- and perfluoroalkyl substances (PFASs) are widely used in industrial products and consumer goods. Due to their extremely recalcitrant nature and potential bioaccumulation and toxicity, exposure to PFASs may result in adverse health outcomes in humans and wildlife. In this study, we developed a...

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Veröffentlicht in:	Analytical chemistry (Washington) 2021-07, Vol.93 (27), p.9634-9639
Hauptverfasser:	Zhang, Quanqing, Dong, Xuejiao, Lu, Jiuwei, Song, Jikui, Wang, Yinsheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkanesulfonic Acids Beads Bioaccumulation Chemistry Chromatography, Liquid Environmental Pollutants Fatty acid-binding protein Fatty Acid-Binding Proteins Fatty acids Fluorocarbons Humans Industrial products Liquid chromatography Lysine Mass spectrometry Mass spectroscopy Peptides Perfluoro compounds Perfluoroalkyl & polyfluoroalkyl substances Perfluorooctane sulfonic acid Perfluorooctanoic acid Proteins Proteome Proteomes Selective binding Stable isotopes Streptavidin Tandem Mass Spectrometry Toxicity Trypsin Wildlife
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