Optimization of loop-mediated isothermal amplification (LAMP) assay for robust visualization in SARS-CoV-2 and emerging variants diagnosis

[Display omitted] •The colorimetric LAMP tool is rapid (40 min) and sensitive (10 copies).•The LAMP assay can be stably performed in portable heating devices.•This LAMP assay acts matchable effectiveness to qPCR detection.•This POC test is optimal in the diagnosis of main SARS-CoV-2 variants. Loop-m...

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Veröffentlicht in:	Chemical engineering science 2022-04, Vol.251, p.117430-117430, Article 117430
Hauptverfasser:	Luo, Zhen, Ye, Chunhong, Xiao, Heng, Yin, Jialing, Liang, Yicong, Ruan, Zhihui, Luo, Danju, Gao, Daolong, Tan, Qiuping, Li, Yongkui, Zhang, Qiwei, Liu, Weiyong, Wu, Jianguo
Format:	Artikel
Sprache:	eng
Schlagworte:	Coronavirus disease 2019 (COVID-19) pandemic Emerging SARS-CoV-2 variants Loop-mediated isothermal amplification (LAMP) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis
Online-Zugang:	Volltext
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