STING signaling activation inhibits HBV replication and attenuates the severity of liver injury and HBV-induced fibrosis

The covalently closed circular DNA (cccDNA) of HBV plays a crucial role in viral persistence and is also a risk factor for developing HBV-induced diseases, including liver fibrosis. Stimulator of interferon genes (STING), a master regulator of DNA-mediated innate immune activation, is a potential th...

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