Regulatory Effects of Quercetin on M1/M2 Macrophage Polarization and Oxidative/Antioxidative Balance

Macrophage polarization plays essential and diverse roles in most diseases, such as atherosclerosis, adipose tissue inflammation, and insulin resistance. Homeostasis dysfunction in M1/M2 macrophage polarization causes pathological conditions and inflammation. Neuroinflammation is characterized by mi...

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Veröffentlicht in:	Nutrients 2021-12, Vol.14 (1), p.67
Hauptverfasser:	Tsai, Cheng-Fang, Chen, Guan-Wei, Chen, Yen-Chang, Shen, Ching-Kai, Lu, Dah-Yuu, Yang, Liang-Yo, Chen, Jia-Hong, Yeh, Wei-Lan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue AKT protein AMP-activated protein kinase Animal cognition Animals Antibodies Antioxidants Antioxidants - pharmacology Arteriosclerosis Atherosclerosis Cell Polarity - drug effects Cell Polarity - physiology Central nervous system Chemokines Cyclooxygenase 2 - metabolism Cyclooxygenase-2 Cysteine Cytokines Dietary supplements Enzymes Flavonoids Gene amplification Glutamate-cysteine ligase Heme Heme Oxygenase-1 - metabolism Homeostasis Inflammation Inflammation - chemically induced Inflammation - drug therapy Inflammation - metabolism Inflammatory diseases Insulin Insulin resistance Interleukin 10 Ligands Lipopolysaccharides - toxicity Macrophage Activation Macrophages Macrophages - metabolism Markers Mental disorders Metabolism Mice Microglia Microglia - drug effects Microglia - metabolism Morphology Neurodegeneration NF-E2-Related Factor 2 - metabolism Nitric oxide Nitric Oxide Synthase Type II - metabolism Oxidative stress Oxidative Stress - drug effects Oxidoreductase Phagocytosis Polarization Prostaglandin endoperoxide synthase Quercetin - pharmacology Quinones RAW 264.7 Cells Reactive oxygen species Signal Transduction - drug effects Statistical analysis Tumor Necrosis Factor-alpha - metabolism
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