TNF-α-Mediated RIPK1 Pathway Participates in the Development of Trigeminal Neuropathic Pain in Rats

Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) participates in the regulation of cellular stress and inflammatory responses, but its function in neuropathic pain remains poorly understood. This study evaluated the role of RIPK1 in neuropathic pain following inferior alveolar nerve in...

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Veröffentlicht in:	International journal of molecular sciences 2022-01, Vol.23 (1), p.506
Hauptverfasser:	Son, Jo Young, Ju, Jin Sook, Kim, Yu Mi, Ahn, Dong Kuk
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveoli Animals Antibodies Astrocytes Astrocytes - metabolism Cellular stress response Dental implants Dental prosthetics Disease Models, Animal Gene Expression Regulation Hyperalgesia - genetics Hyperalgesia - metabolism Immunofluorescence Inflammation Injury prevention Kinases Localization Male Neuralgia Pain Pain perception Protein kinase Proteins Rats Rats, Sprague-Dawley Receptor-Interacting Protein Serine-Threonine Kinases - genetics Receptor-Interacting Protein Serine-Threonine Kinases - metabolism Signal Transduction Spinal cord Spinal trigeminal nucleus Therapeutic targets Trigeminal Neuralgia - genetics Trigeminal Neuralgia - metabolism Tumor necrosis factor receptors Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF Tumor necrosis factor-α
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