Down-Regulation of miR-194-5p for Predicting Metastasis in Breast Cancer Cells

MicroRNAs (miRNAs), as key negative regulators of gene expression, are closely related to tumor occurrence and progression. miR-194-5p (miR-194-1) has been shown to play a regulatory role in various cancers however, its biological function and mechanism of action in breast cancer have not yet been w...

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Veröffentlicht in:	International journal of molecular sciences 2021-12, Vol.23 (1), p.325
Hauptverfasser:	Yen, Yu-Ting, Yang, Jou-Chun, Chang, Jiun-Bo, Tsai, Shih-Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying Base Sequence Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer therapies Cell adhesion & migration Cell Line, Tumor Cell Movement - genetics Down-Regulation - genetics Drug resistance Enzymes Estrogens Female Gelatin Gelatinase A Gelatinase B Gene expression Gene Expression Regulation, Neoplastic Genes Genomes Growth factors Humans Invasiveness Kinases Matrix metalloproteinase Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism Matrix metalloproteinases Medical prognosis Mesenchyme Metalloproteinase Metastases Metastasis MicroRNAs - genetics MicroRNAs - metabolism miRNA Models, Biological Neoplasm Invasiveness Neoplasm Metastasis Neoplasm Proteins - metabolism Protein synthesis Proteins Survival Analysis Transcription Tumors Vimentin Western blotting Wound healing Zonula occludens-1 protein
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