Needleless Ablation of Osteoid Osteoma and Osteoblastoma: The Emergent Role of MRgFUS
Osteoblastoma (OB) and osteoid osteoma (OO) are benign bone-forming tumors, with nearly identical basic microscopic features. The main difference is dimension (OO has usually a nidus measuring
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creator | Cobianchi Bellisari, Flavia Palumbo, Pierpaolo Masciocchi, Carlo Zoccali, Carmine Barile, Antonio Arrigoni, Francesco |
description | Osteoblastoma (OB) and osteoid osteoma (OO) are benign bone-forming tumors, with nearly identical basic microscopic features. The main difference is dimension (OO has usually a nidus measuring |
doi_str_mv | 10.3390/jcm11010128 |
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The main difference is dimension (OO has usually a nidus measuring <2 cm in diameter). In addition, OB is biologically more active than OO, with a tendency to grow in size. Historically, treatments have included surgical resection and analgesics, although invasiveness and poor tolerance have led to the current standard of care moving toward interventional radiology, where radiofrequency ablation (RFA) represents the most diffuse technique. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) has recently emerged as another innovative alternative treatment, providing tumor ablation through a needleless and ionizing radiation-free modality. In addition, this technique has the ability to guarantee a very precise and controlled increase in temperature, delivering small amounts of energy that can accurately destroy only the lesion, avoiding healthy surrounding tissues. The present review focuses on MRgFUS as the less invasive, safe, effective, and durable treatment option for the management of osteoid osteoma and osteoblastoma, including a description of technical details, indications and outcomes.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm11010128</identifier><identifier>PMID: 35011867</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Ablation ; Bone cancer ; Bones ; Clinical medicine ; Energy ; Heat ; Pain ; Radiation ; Review ; Skin ; Success ; Surgery ; Tumors ; Ultrasonic imaging</subject><ispartof>Journal of clinical medicine, 2021-12, Vol.11 (1), p.128</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). 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The present review focuses on MRgFUS as the less invasive, safe, effective, and durable treatment option for the management of osteoid osteoma and osteoblastoma, including a description of technical details, indications and outcomes.</description><subject>Ablation</subject><subject>Bone cancer</subject><subject>Bones</subject><subject>Clinical medicine</subject><subject>Energy</subject><subject>Heat</subject><subject>Pain</subject><subject>Radiation</subject><subject>Review</subject><subject>Skin</subject><subject>Success</subject><subject>Surgery</subject><subject>Tumors</subject><subject>Ultrasonic imaging</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkd1LwzAUxYMobsw9-S4FXwSZ5qNNUh-EMTYVpoO5PYe0ud062mY2neB_b-bmmCYP95L87uFcDkKXBN8xFuP7VVoSgv2l8gS1KRaih5lkp0d9C3WdW2F_pAwpEeeoxSJMiOSijeZvAKaAApwL-kmhm9xWgc2CiWvA5mZXSx3oat97xjX-5SGYLSEYllAvoGqCqS1gO_c6XYzm7xfoLNOFg-6-dtB8NJwNnnvjydPLoD_upSGOmx4ljCVxmAnNaURJmhghBKZhbAzjkgnCtQFDCRYhp1hrwUOcQhqDISFLJGUd9LjTXW-SEkzqndS6UOs6L3X9pazO1d-fKl-qhf1UUoQR5sIL3OwFavuxAdeoMncpFIWuwG6copzIGPMYb9Hrf-jKburKr_dDURb5JTx1u6PS2jpXQ3YwQ7DaJqaOEvP01bH_A_ubD_sG0RePbQ</recordid><startdate>20211227</startdate><enddate>20211227</enddate><creator>Cobianchi Bellisari, Flavia</creator><creator>Palumbo, Pierpaolo</creator><creator>Masciocchi, Carlo</creator><creator>Zoccali, Carmine</creator><creator>Barile, Antonio</creator><creator>Arrigoni, Francesco</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-1514-0092</orcidid><orcidid>https://orcid.org/0000-0001-7793-1872</orcidid><orcidid>https://orcid.org/0000-0002-4239-4066</orcidid></search><sort><creationdate>20211227</creationdate><title>Needleless Ablation of Osteoid Osteoma and Osteoblastoma: The Emergent Role of MRgFUS</title><author>Cobianchi Bellisari, Flavia ; Palumbo, Pierpaolo ; Masciocchi, Carlo ; Zoccali, Carmine ; Barile, Antonio ; Arrigoni, Francesco</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c409t-2133b94f7a62521cbd7770249dd3683716aded21074620aa7640cec9ed143b823</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Ablation</topic><topic>Bone cancer</topic><topic>Bones</topic><topic>Clinical medicine</topic><topic>Energy</topic><topic>Heat</topic><topic>Pain</topic><topic>Radiation</topic><topic>Review</topic><topic>Skin</topic><topic>Success</topic><topic>Surgery</topic><topic>Tumors</topic><topic>Ultrasonic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cobianchi Bellisari, Flavia</creatorcontrib><creatorcontrib>Palumbo, Pierpaolo</creatorcontrib><creatorcontrib>Masciocchi, Carlo</creatorcontrib><creatorcontrib>Zoccali, Carmine</creatorcontrib><creatorcontrib>Barile, Antonio</creatorcontrib><creatorcontrib>Arrigoni, Francesco</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cobianchi Bellisari, Flavia</au><au>Palumbo, Pierpaolo</au><au>Masciocchi, Carlo</au><au>Zoccali, Carmine</au><au>Barile, Antonio</au><au>Arrigoni, Francesco</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Needleless Ablation of Osteoid Osteoma and Osteoblastoma: The Emergent Role of MRgFUS</atitle><jtitle>Journal of clinical medicine</jtitle><addtitle>J Clin Med</addtitle><date>2021-12-27</date><risdate>2021</risdate><volume>11</volume><issue>1</issue><spage>128</spage><pages>128-</pages><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>Osteoblastoma (OB) and osteoid osteoma (OO) are benign bone-forming tumors, with nearly identical basic microscopic features. 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subjects | Ablation Bone cancer Bones Clinical medicine Energy Heat Pain Radiation Review Skin Success Surgery Tumors Ultrasonic imaging |
title | Needleless Ablation of Osteoid Osteoma and Osteoblastoma: The Emergent Role of MRgFUS |
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