The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans

Abstract Zinc cluster transcription factors (TFs) are essential fungal regulators of gene expression. In the pathogen Candida albicans, the gene orf19.1604 encodes a zinc cluster TF regulating filament development. Hyperactivation of orf19.1604, which we have named RHA1 for Regulator of Hyphal Activ...

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Veröffentlicht in:	Genetics (Austin) 2022-01, Vol.220 (1)
Hauptverfasser:	Parvizi Omran, Raha, Ramírez-Zavala, Bernardo, Aji Tebung, Walters, Yao, Shuangyan, Feng, Jinrong, Law, Chris, Dumeaux, Vanessa, Morschhäuser, Joachim, Whiteway, Malcolm
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biofilms Biofilms - growth & development BRG1 protein Candida albicans Candida albicans - genetics Candida albicans - metabolism Candida albicans - pathogenicity Candidiasis - microbiology Clusters Disseminated infection Filamentation Fungal Proteins - genetics Fungal Proteins - metabolism Gene expression Gene Expression Regulation, Fungal Gene regulation Genetics Growth conditions Hyperactivity Hyphae - genetics Hyphae - growth & development Hyphae - metabolism Inactivation Invasiveness Investigation Mice Morphogenesis Mutants Transcription factors Transcription Factors - genetics Transcription Factors - metabolism Virulence Virulence - genetics Zinc
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