Diagnostic Characteristics of Lactate Dehydrogenase on a Multiplex Assay for Malaria Detection Including the Zoonotic Parasite Plasmodium knowlesi

Plasmodium lactate dehydrogenase (pLDH) is a common target in malaria rapid diagnostic tests (RDTs). These commercial antibody capture assays target either Plasmodium falciparum-specific pLDH (PfLDH), P. vivax-specific pLDH (PvLDH), or a conserved epitope in all human malaria pLDH (PanLDH). However,...

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Veröffentlicht in:	The American journal of tropical medicine and hygiene 2022-01, Vol.106 (1), p.275-282
Hauptverfasser:	Barney, Rebecca, Velasco, Miguel, Cooper, Caitlin A, Rashid, Andrew, Kyle, Dennis E, Moon, Robert W, Domingo, Gonzalo J, Jang, Ihn Kyung
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Protozoan - analysis Cross Reactions Dehydrogenases Erythrocytes Humans L-Lactate Dehydrogenase - blood L-Lactate Dehydrogenase - metabolism Malaria Malaria - diagnosis Plasmodium knowlesi - enzymology Plasmodium knowlesi - isolation & purification Species Specificity Zoonoses Zoonoses - diagnosis Zoonoses - parasitology
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