Modifying strategies for SDF-1/CXCR4 interaction during mesenchymal stem cell transplantation

Mesenchymal stem cell (MSC) transplantation is regarded as a promising candidate for the treatment of ischaemic heart disease. The major hurdles for successful clinical translation of MSC therapy are poor survival, retention, and engraftment in the infarcted heart. Stromal cell-derived factor-1/chem...

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Veröffentlicht in:	General thoracic and cardiovascular surgery 2022-01, Vol.70 (1), p.1-10
Hauptverfasser:	Jiang, Qin, Huang, Keli, Lu, Fang, Deng, Shaoping, Yang, Zhenglin, Hu, Shengshou
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cardiac function Cardiac Surgery Cardiology Chemokine CXCL12 Chemokines Clinical trials Extracellular vesicles Granulocytes Heart Hormones Humans Hypoxia Ischemia Medicine Medicine & Public Health Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells Myocardial Infarction Myocardial Ischemia Peptides Proteins Receptors, CXCR4 - genetics Review Review Article Stem cell transplantation Stem cells Surgical Oncology Thoracic Surgery Ultrasonic imaging
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