Rapid pathogen-specific recruitment of immune effector cells in the skin by secreted toxins

Swift recruitment of phagocytic leucocytes is critical in preventing infection when bacteria breach through the protective layers of the skin. According to canonical models, this occurs via an indirect process that is initiated by contact of bacteria with resident skin cells and which is independent...

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Veröffentlicht in:Nature microbiology 2022-01, Vol.7 (1), p.62-72
Hauptverfasser: Nguyen, Thuan H., Cheung, Gordon Y. C., Rigby, Kevin M., Kamenyeva, Olena, Kabat, Juraj, Sturdevant, Daniel E., Villaruz, Amer E., Liu, Ryan, Piewngam, Pipat, Porter, Adeline R., Firdous, Saba, Chiou, Janice, Park, Matthew D., Hunt, Rachelle L., Almufarriji, Fawaz M. F., Tan, Vee Y., Asiamah, Titus K., McCausland, Joshua W., Fisher, Emilie L., Yeh, Anthony J., Bae, Justin S., Kobayashi, Scott D., Wang, Ji Ming, Barber, Daniel L., DeLeo, Frank R., Otto, Michael
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Sprache:eng
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