GPEdit: the genetic and pharmacogenomic landscape of A-to-I RNA editing in cancers

Abstract Altered A-to-I RNA editing has been widely observed in many human cancers and some editing sites are associated with drug sensitivity, implicating its therapeutic potential. Increasing evidence has demonstrated that a quantitative trait loci mapping approach is effective to understanding th...

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Veröffentlicht in:	Nucleic acids research 2022-01, Vol.50 (D1), p.D1231-D1237
Hauptverfasser:	Ruan, Hang, Li, Qiang, Liu, Yuan, Liu, Yaoming, Lussier, Charles, Diao, Lixia, Han, Leng
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Antineoplastic Agents - classification Antineoplastic Agents - therapeutic use Database Issue Databases, Factual Genome-Wide Association Study Humans Neoplasms - drug therapy Neoplasms - genetics Neoplasms - pathology Pharmacogenetics Quantitative Trait Loci - genetics RNA Editing - genetics Transcriptome - drug effects
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