Diacerein, an inhibitor of IL-1β downstream mediated apoptosis, improves radioimmunotherapy in a mouse model of Burkitt's lymphoma

Lymphoma has the characteristics of a solid tumor. Penetration of monoclonal antibodies is limited in solid tumors during radioimmunotherapy (RIT). Here, we first investigated the use of diacerein (DIA) as a combination drug to improve the penetration and therapeutic efficacy of I-rituximab (RTX) us...

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Veröffentlicht in:	American journal of cancer research 2021-01, Vol.11 (12), p.6147-6159
Hauptverfasser:	Zaheer, Javeria, Yu, A Ram, Kim, Hyeongi, Kang, Hyun Ji, Kang, Min Kyoung, Lee, Jae Jun, Kim, Jin Su
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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