Transcriptome analysis to identify the downstream genes of androgen receptor in dermal papilla cells

Testosterone signaling mediates various diseases, such as androgenetic alopecia and prostate cancer. Testosterone signaling is mediated by the androgen receptor (AR). In this study, we fortuitously found that primary and immortalized dermal papilla cells suppressed AR expression, although dermal pap...

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Veröffentlicht in:	BMC genetics 2022-01, Vol.23 (1), p.2-2, Article 2
Hauptverfasser:	Furuya, Kai, Fujibayashi, So, Wu, Tao, Takahashi, Kouhei, Takase, Shin, Orimoto, Ai, Sugano, Eriko, Tomita, Hiroshi, Kashiwagi, Sayo, Kiyono, Tohru, Ishii, Tsuyoshi, Fukuda, Tomokazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Alopecia Androgen receptors Androgens Bioinformatics Caveolin Caveolin 1 - genetics Caveolin-1 Cellular signal transduction Comparative analysis Connective tissue cells Cyclin-dependent kinases Gene expression Gene Expression Profiling Genetic aspects Genomes Health aspects Humans Kinases Ligands Male Medical research Medicine, Experimental Prostate cancer Receptors, Androgen - genetics Reproducibility RNA RNA polymerase RNA sequencing Signal transduction Skin Stem cells Testosterone Testosterone Congeners Therapeutic targets Transcriptome - genetics Transcriptomes
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