Synaptic protein interaction networks encode experience by assuming stimulus-specific and brain-region-specific states

A core network of widely expressed proteins within the glutamatergic post-synapse mediates activity-dependent synaptic plasticity throughout the brain, but the specific proteomic composition of synapses differs between brain regions. Here, we address the question, how does proteomic composition affe...

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Veröffentlicht in:	Cell reports (Cambridge) 2021-11, Vol.37 (9), p.110076-110076, Article 110076
Hauptverfasser:	Lautz, Jonathan D, Tsegay, Kaleb B, Zhu, Zhiyi, Gniffke, Edward P, Welsh, John P, Smith, Stephen E P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blinking - drug effects Brain - drug effects Brain - metabolism Conditioning, Eyelid Excitatory Amino Acid Agonists - pharmacology Female Male Methoxyhydroxyphenylglycol - analogs & derivatives Methoxyhydroxyphenylglycol - pharmacology Mice N-Methylaspartate - pharmacology Neuronal Plasticity Protein Interaction Maps Proteome - analysis Proteome - metabolism Synapses - drug effects Synapses - metabolism
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