Conceptual combination of disinfection in regenerative endodontics: Conventional versus laser-assisted disinfection
Background: Successful regeneration depends on four key elements of tissue engineering such as stem cells, growth factors, scaffold and sterile environment. Therefore, regenerative endodontic therapy requires higher degree of disinfection for successful outcomes. Aims and Objective: To evaluate the...
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| Veröffentlicht in: | Journal of conservative dentistry 2021-05, Vol.24 (3), p.252-259 |
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| creator | Divya, D Naik, Saraswathi Raju, O Shivani, Bellal Basappa, N Betur, Archana |
| description | Background: Successful regeneration depends on four key elements of tissue engineering such as stem cells, growth factors, scaffold and sterile environment. Therefore, regenerative endodontic therapy requires higher degree of disinfection for successful outcomes.
Aims and Objective: To evaluate the clinical and radiographic outcome using conventional and laser assisted disinfection in regenerative endodontics at 1, 3 and 6 months.
Materials and Methods: 18 children with necrotic young permanent teeth were selected for the study. In Group A, in the first appointment AAE (American Association of Endodontics, Clinical Consideration for Regenerative Endodontic Procedure - 2016) disinfection protocol was employed. In Group B laser assisted disinfection (810 nm diode laser, 1 W, 20 ms Pulse length and 20 ms interval duration) was performed. Microbial samples were obtained before and after disinfection to check the level of disinfection. The cases were followed up at 1 month, 3 months and 6 months interval and evaluated for clinical outcome, periapical healing and apical response. Data were statistically analyzed with level of significance set 1% or 5% accordingly (P |
| doi_str_mv | 10.4103/jcd.jcd_96_21 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8717846</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A686930643</galeid><sourcerecordid>A686930643</sourcerecordid><originalsourceid>FETCH-LOGICAL-c484u-9f4cf4b01dcd8cf3363673b193ec64f16f228489e339e43512171746242a2e0c3</originalsourceid><addsrcrecordid>eNptkl1v0zAUhiMEYmNwyS2KhIS4SfFXnJiLoaniS5rEDVxbrnPSunPtYiet-PecrFtZ0RRFsePHj5Nz3qJ4TclMUMI_rG03w1srqRl9UpwT1YiqZoQ_vR2zijSkOSte5LwmRAqhyPPijNeE17Qm50Wex2BhO4zGlzZuFi6YwcVQxr7sXHahB3s7d6FMsIQACdd3UELoYhfD4Gz-WKJjB2Hi0LKDlMdcepMhVSZnlwfoTmQvi2e98Rle3T0vil9fPv-cf6uuf3z9Pr-6rqxoxVipXtheLAjtbNfannPJZcMXVHGwUvRU9oy1olXAuQKB_8NoQxshmWCGAbH8org8eLfjYgOdxU9MxuttchuT_uhonD5dCW6ll3GnW_S0QqLg_Z0gxd8j5EFvXLbgvQkQx6yZZKSpFWMc0bf_oes4JqzHRGGfeKuI-kctjQeNBYl4rp2k-kq2UnHs0OSaPULh1cHG2Rigd_j-ZMO7BxtWYPywytGPU7HzKVgdQJtizgn6YzEo0VOc9BSlY5yQf_Owgkf6Pj8IfDoA--gHbPyNH_eQNLI3Ie4ft2pWM30fO_4XplneBA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2610338909</pqid></control><display><type>article</type><title>Conceptual combination of disinfection in regenerative endodontics: Conventional versus laser-assisted disinfection</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Divya, D ; Naik, Saraswathi ; Raju, O ; Shivani, Bellal ; Basappa, N ; Betur, Archana</creator><creatorcontrib>Divya, D ; Naik, Saraswathi ; Raju, O ; Shivani, Bellal ; Basappa, N ; Betur, Archana</creatorcontrib><description>Background: Successful regeneration depends on four key elements of tissue engineering such as stem cells, growth factors, scaffold and sterile environment. Therefore, regenerative endodontic therapy requires higher degree of disinfection for successful outcomes.
Aims and Objective: To evaluate the clinical and radiographic outcome using conventional and laser assisted disinfection in regenerative endodontics at 1, 3 and 6 months.
Materials and Methods: 18 children with necrotic young permanent teeth were selected for the study. In Group A, in the first appointment AAE (American Association of Endodontics, Clinical Consideration for Regenerative Endodontic Procedure - 2016) disinfection protocol was employed. In Group B laser assisted disinfection (810 nm diode laser, 1 W, 20 ms Pulse length and 20 ms interval duration) was performed. Microbial samples were obtained before and after disinfection to check the level of disinfection. The cases were followed up at 1 month, 3 months and 6 months interval and evaluated for clinical outcome, periapical healing and apical response. Data were statistically analyzed with level of significance set 1% or 5% accordingly (P<0.01 or P<0.05)
Results: On intragroup comparison there was significant reduction in bacterial count before and after disinfection with respect to laser assisted disinfection group. (P value = 0.007) There was no significant change in the clinical outcome score in laser group at 1,3- and 6-months interval. Periapical healing score showed statistically significant results in laser group when followed from 3 months to 6 months (P value = 0.04).
Conclusion: Along with AAE 2016 protocol, use of laser assisted disinfection resulted in improved quality of disinfection and an expeditious clinical outcome and periapical healing in necrotic young permanent teeth. Keywords: Disinfection; laser; regenerative endodontics; sodium hypochlorite; tooth apex</description><identifier>ISSN: 0972-0707</identifier><identifier>EISSN: 0974-5203</identifier><identifier>DOI: 10.4103/jcd.jcd_96_21</identifier><identifier>PMID: 35035150</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. Ltd</publisher><subject>Clinical outcomes ; Disinfection ; Endodontics ; Ethylenediaminetetraacetic acid ; Growth factors ; Infection control ; Lasers ; Original ; Sodium hypochlorite ; Statistical analysis ; Stem cells ; Teeth ; Tissue engineering ; Transplantation</subject><ispartof>Journal of conservative dentistry, 2021-05, Vol.24 (3), p.252-259</ispartof><rights>Copyright: © 2021 Journal of Conservative Dentistry.</rights><rights>COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd.</rights><rights>2021. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2021 Journal of Conservative Dentistry 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c484u-9f4cf4b01dcd8cf3363673b193ec64f16f228489e339e43512171746242a2e0c3</citedby><cites>FETCH-LOGICAL-c484u-9f4cf4b01dcd8cf3363673b193ec64f16f228489e339e43512171746242a2e0c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717846/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717846/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27928,27929,53795,53797</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35035150$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Divya, D</creatorcontrib><creatorcontrib>Naik, Saraswathi</creatorcontrib><creatorcontrib>Raju, O</creatorcontrib><creatorcontrib>Shivani, Bellal</creatorcontrib><creatorcontrib>Basappa, N</creatorcontrib><creatorcontrib>Betur, Archana</creatorcontrib><title>Conceptual combination of disinfection in regenerative endodontics: Conventional versus laser-assisted disinfection</title><title>Journal of conservative dentistry</title><addtitle>J Conserv Dent</addtitle><description>Background: Successful regeneration depends on four key elements of tissue engineering such as stem cells, growth factors, scaffold and sterile environment. Therefore, regenerative endodontic therapy requires higher degree of disinfection for successful outcomes.
Aims and Objective: To evaluate the clinical and radiographic outcome using conventional and laser assisted disinfection in regenerative endodontics at 1, 3 and 6 months.
Materials and Methods: 18 children with necrotic young permanent teeth were selected for the study. In Group A, in the first appointment AAE (American Association of Endodontics, Clinical Consideration for Regenerative Endodontic Procedure - 2016) disinfection protocol was employed. In Group B laser assisted disinfection (810 nm diode laser, 1 W, 20 ms Pulse length and 20 ms interval duration) was performed. Microbial samples were obtained before and after disinfection to check the level of disinfection. The cases were followed up at 1 month, 3 months and 6 months interval and evaluated for clinical outcome, periapical healing and apical response. Data were statistically analyzed with level of significance set 1% or 5% accordingly (P<0.01 or P<0.05)
Results: On intragroup comparison there was significant reduction in bacterial count before and after disinfection with respect to laser assisted disinfection group. (P value = 0.007) There was no significant change in the clinical outcome score in laser group at 1,3- and 6-months interval. Periapical healing score showed statistically significant results in laser group when followed from 3 months to 6 months (P value = 0.04).
Conclusion: Along with AAE 2016 protocol, use of laser assisted disinfection resulted in improved quality of disinfection and an expeditious clinical outcome and periapical healing in necrotic young permanent teeth. 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Naik, Saraswathi ; Raju, O ; Shivani, Bellal ; Basappa, N ; Betur, Archana</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484u-9f4cf4b01dcd8cf3363673b193ec64f16f228489e339e43512171746242a2e0c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Clinical outcomes</topic><topic>Disinfection</topic><topic>Endodontics</topic><topic>Ethylenediaminetetraacetic acid</topic><topic>Growth factors</topic><topic>Infection control</topic><topic>Lasers</topic><topic>Original</topic><topic>Sodium hypochlorite</topic><topic>Statistical analysis</topic><topic>Stem cells</topic><topic>Teeth</topic><topic>Tissue engineering</topic><topic>Transplantation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Divya, D</creatorcontrib><creatorcontrib>Naik, Saraswathi</creatorcontrib><creatorcontrib>Raju, O</creatorcontrib><creatorcontrib>Shivani, Bellal</creatorcontrib><creatorcontrib>Basappa, N</creatorcontrib><creatorcontrib>Betur, Archana</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of conservative dentistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Divya, D</au><au>Naik, Saraswathi</au><au>Raju, O</au><au>Shivani, Bellal</au><au>Basappa, N</au><au>Betur, Archana</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Conceptual combination of disinfection in regenerative endodontics: Conventional versus laser-assisted disinfection</atitle><jtitle>Journal of conservative dentistry</jtitle><addtitle>J Conserv Dent</addtitle><date>2021-05-01</date><risdate>2021</risdate><volume>24</volume><issue>3</issue><spage>252</spage><epage>259</epage><pages>252-259</pages><issn>0972-0707</issn><eissn>0974-5203</eissn><abstract>Background: Successful regeneration depends on four key elements of tissue engineering such as stem cells, growth factors, scaffold and sterile environment. Therefore, regenerative endodontic therapy requires higher degree of disinfection for successful outcomes.
Aims and Objective: To evaluate the clinical and radiographic outcome using conventional and laser assisted disinfection in regenerative endodontics at 1, 3 and 6 months.
Materials and Methods: 18 children with necrotic young permanent teeth were selected for the study. In Group A, in the first appointment AAE (American Association of Endodontics, Clinical Consideration for Regenerative Endodontic Procedure - 2016) disinfection protocol was employed. In Group B laser assisted disinfection (810 nm diode laser, 1 W, 20 ms Pulse length and 20 ms interval duration) was performed. Microbial samples were obtained before and after disinfection to check the level of disinfection. The cases were followed up at 1 month, 3 months and 6 months interval and evaluated for clinical outcome, periapical healing and apical response. Data were statistically analyzed with level of significance set 1% or 5% accordingly (P<0.01 or P<0.05)
Results: On intragroup comparison there was significant reduction in bacterial count before and after disinfection with respect to laser assisted disinfection group. (P value = 0.007) There was no significant change in the clinical outcome score in laser group at 1,3- and 6-months interval. Periapical healing score showed statistically significant results in laser group when followed from 3 months to 6 months (P value = 0.04).
Conclusion: Along with AAE 2016 protocol, use of laser assisted disinfection resulted in improved quality of disinfection and an expeditious clinical outcome and periapical healing in necrotic young permanent teeth. Keywords: Disinfection; laser; regenerative endodontics; sodium hypochlorite; tooth apex</abstract><cop>India</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>35035150</pmid><doi>10.4103/jcd.jcd_96_21</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central |
| subjects | Clinical outcomes Disinfection Endodontics Ethylenediaminetetraacetic acid Growth factors Infection control Lasers Original Sodium hypochlorite Statistical analysis Stem cells Teeth Tissue engineering Transplantation |
| title | Conceptual combination of disinfection in regenerative endodontics: Conventional versus laser-assisted disinfection |
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