Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time

Using spectroscopic rulers to track multiple conformations of single biomolecules and their dynamics have revolutionized the understanding of structural dynamics and its contributions to biology. While the FRET-based ruler reports on inter-dye distances in the 3-10 nm range, other spectroscopic tech...

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Veröffentlicht in:	Journal of visualized experiments 2021-05 (171)
Hauptverfasser:	Zaer, Sofia, Lerner, Eitan
Format:	Artikel
Sprache:	eng
Schlagworte:	Fluorescence Resonance Energy Transfer Intrinsically Disordered Proteins Macromolecular Substances Molecular Conformation Synucleins
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