Hsa_circ_0008259 modulates miR-21-5p and PDCD4 expression to restrain osteosarcoma progression

Osteosarcoma (OS) is one of the most common primary bone tumors in children and adolescents. However, the molecular mechanism of OS tumorigenesis is still little known. Circular RNA (circRNA) is a key player in the progression of many cancers. This study is performed to decipher the role and mechani...

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Veröffentlicht in:	Aging (Albany, NY.) NY.), 2021-12, Vol.13 (23), p.25484-25495
Hauptverfasser:	Guan, Kai, Liu, Shizhang, Duan, Keke, Zhang, Xiaoxia, Liu, Huitong, Xu, Bingqiang, Wang, Xi, Jin, Xin
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Regulatory Proteins - metabolism Bone Neoplasms - metabolism Bone Neoplasms - pathology Cell Line, Tumor Disease Progression Down-Regulation Humans MicroRNAs - metabolism Osteosarcoma - metabolism Osteosarcoma - pathology Real-Time Polymerase Chain Reaction Research Paper RNA, Circular - metabolism RNA-Binding Proteins - metabolism
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