Lipids and Trehalose Actively Cooperate in Heat Stress Management of Schizosaccharomyces pombe

Homeostatic maintenance of the physicochemical properties of cellular membranes is essential for life. In yeast, trehalose accumulation and lipid remodeling enable rapid adaptation to perturbations, but their crosstalk was not investigated. Here we report about the first in-depth, mass spectrometry-...

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Veröffentlicht in:	International journal of molecular sciences 2021-12, Vol.22 (24), p.13272
Hauptverfasser:	Péter, Mária, Gudmann, Péter, Kóta, Zoltán, Török, Zsolt, Vígh, László, Glatz, Attila, Balogh, Gábor
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell cycle Cell membranes Crosstalk Enzymes Glucose Glucosyltransferases - genetics Glucosyltransferases - metabolism Heat Heat stress Homeostasis Hot Temperature Lipidomics - methods Lipids Mass Spectrometry Mass spectroscopy Metabolism Metabolites Mutation Oleic acid Oleic Acid - metabolism Phosphoric Monoester Hydrolases - genetics Phosphoric Monoester Hydrolases - metabolism Physicochemical properties Proteins Schizosaccharomyces - genetics Schizosaccharomyces - growth & development Schizosaccharomyces - metabolism Schizosaccharomyces pombe Schizosaccharomyces pombe Proteins - genetics Schizosaccharomyces pombe Proteins - metabolism Scientific imaging Sensors Stearic acid Trehalose Trehalose - metabolism Triglycerides Triglycerides - metabolism Yeast
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