Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics

The paramount importance of a healthy diet in the prevention of type 2 diabetes is now well recognized. Blueberries (BBs) have been described as attractive functional fruits for this purpose. This study aimed to elucidate the cellular and molecular mechanisms pertaining to the protective impact of b...

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Veröffentlicht in:	Nutrients 2021-11, Vol.13 (12), p.4192
Hauptverfasser:	Nunes, Sara, Viana, Sofia D, Preguiça, Inês, Alves, André, Fernandes, Rosa, Teodoro, João S, Matos, Patrícia, Figueirinha, Artur, Salgueiro, Lígia, André, Alexandra, Silva, Sara, Jarak, Ivana, Carvalho, Rui A, Cavadas, Cláudia, Rolo, Anabela P, Palmeira, Carlos M, Pintado, Maria M, Reis, Flávio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants Bioenergetics Blood Glucose - drug effects Blueberries Blueberry Plants Complications Composition Deregulation Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - prevention & control Diet Digestive system Disease Models, Animal Drinking water Endotoxemia Energy Intake - drug effects Energy Metabolism - drug effects Fatty liver Fruit and Vegetable Juices Gastrointestinal Microbiome - drug effects Glucose Glucose tolerance Hypertriglyceridemia Insulin Insulin - blood Insulin Resistance Intestinal microflora Ketogenesis Lipid Metabolism - drug effects Lipids Lipids - blood Liver Liver - metabolism Metabolic disorders Metabolites Microbiota Mitochondria Mitochondria - metabolism Molecular modelling Oxidation Phytochemicals Prediabetic State - metabolism Rats Steatosis Sucrose Ultrasonic imaging Veins & arteries
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