The Carbohydrate Metabolism of Lactiplantibacillus plantarum
has a strong carbohydrate utilization ability. This characteristic plays an important role in its gastrointestinal tract colonization and probiotic effects. LP-F1 presents a high carbohydrate utilization capacity. The genome analysis of 165 strains indicated the species has a plenty of carbohydrate...
Gespeichert in:
| Veröffentlicht in: | International journal of molecular sciences 2021-12, Vol.22 (24), p.13452 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 24 |
| container_start_page | 13452 |
| container_title | International journal of molecular sciences |
| container_volume | 22 |
| creator | Cui, Yanhua Wang, Meihong Zheng, Yankun Miao, Kai Qu, Xiaojun |
| description | has a strong carbohydrate utilization ability. This characteristic plays an important role in its gastrointestinal tract colonization and probiotic effects.
LP-F1 presents a high carbohydrate utilization capacity. The genome analysis of 165
strains indicated the species has a plenty of carbohydrate metabolism genes, presenting a strain specificity. Furthermore, two-component systems (TCSs) analysis revealed that the species has more TCSs than other lactic acid bacteria, and the distribution of TCS also shows the strain specificity. In order to clarify the sugar metabolism mechanism under different carbohydrate fermentation conditions, the expressions of 27 carbohydrate metabolism genes, catabolite control protein A (CcpA) gene
and TCSs genes were analyzed by quantitative real-time PCR technology. The correlation analysis between the expressions of regulatory genes and sugar metabolism genes showed that some regulatory genes were correlated with most of the sugar metabolism genes, suggesting that some TCSs might be involved in the regulation of sugar metabolism. |
| doi_str_mv | 10.3390/ijms222413452 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8704671</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2612810590</sourcerecordid><originalsourceid>FETCH-LOGICAL-c415t-7698e2bfcd33f3d5efdbec4efeef7c90c13a1213c1e41531e265999b3175076d3</originalsourceid><addsrcrecordid>eNpdkctLAzEQxoMotlaPXmXBi5fVvPYREEGKL6h4qeeQzU5sym5Tk12h_72prdJ6mhnmx8d88yF0TvA1YwLf2HkbKKWcMJ7RAzQknNIU47w43OkH6CSEOcaU0UwcowHjgpeUiyG6nc4gGStfudmq9qqD5BU6VbnGhjZxJpko3dlloxadrZS2TdOH5GdUvm9P0ZFRTYCzbR2h98eH6fg5nbw9vYzvJ6nmJOvSIhcl0MromjHD6gxMXYHmYABMoQXWhClCCdMEIs8I0DwTQlSMFBku8pqN0N1Gd9lXLdQaFp1XjVx62yq_kk5Zub9Z2Jn8cF-yLDDPCxIFrrYC3n32EDrZ2qChiUbA9UHSPL6KlVjwiF7-Q-eu94tob03RkuBM4EilG0p7F4IH83cMwXKdi9zLJfIXuw7-6N8g2DfFR4nS</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2612810590</pqid></control><display><type>article</type><title>The Carbohydrate Metabolism of Lactiplantibacillus plantarum</title><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Cui, Yanhua ; Wang, Meihong ; Zheng, Yankun ; Miao, Kai ; Qu, Xiaojun</creator><creatorcontrib>Cui, Yanhua ; Wang, Meihong ; Zheng, Yankun ; Miao, Kai ; Qu, Xiaojun</creatorcontrib><description>has a strong carbohydrate utilization ability. This characteristic plays an important role in its gastrointestinal tract colonization and probiotic effects.
LP-F1 presents a high carbohydrate utilization capacity. The genome analysis of 165
strains indicated the species has a plenty of carbohydrate metabolism genes, presenting a strain specificity. Furthermore, two-component systems (TCSs) analysis revealed that the species has more TCSs than other lactic acid bacteria, and the distribution of TCS also shows the strain specificity. In order to clarify the sugar metabolism mechanism under different carbohydrate fermentation conditions, the expressions of 27 carbohydrate metabolism genes, catabolite control protein A (CcpA) gene
and TCSs genes were analyzed by quantitative real-time PCR technology. The correlation analysis between the expressions of regulatory genes and sugar metabolism genes showed that some regulatory genes were correlated with most of the sugar metabolism genes, suggesting that some TCSs might be involved in the regulation of sugar metabolism.</description><identifier>ISSN: 1422-0067</identifier><identifier>ISSN: 1661-6596</identifier><identifier>EISSN: 1422-0067</identifier><identifier>DOI: 10.3390/ijms222413452</identifier><identifier>PMID: 34948249</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Bacteria ; Biosynthesis ; Carbohydrate metabolism ; Carbohydrate Metabolism - physiology ; Carbohydrates ; Chromosomes ; Correlation analysis ; Enzymes ; Fermentation ; Gastrointestinal system ; Gastrointestinal tract ; Genes ; Genomes ; Kinases ; Lactic acid ; Lactic acid bacteria ; Lactiplantibacillus plantarum ; Lactobacillaceae - metabolism ; Lactobacillus - metabolism ; Lactobacillus plantarum - metabolism ; Lactose ; Metabolism ; Milk ; Peptides ; Phylogenetics ; Prebiotics ; Probiotics ; Protein A ; Protein turnover ; Proteins ; Signal transduction ; Sugar</subject><ispartof>International journal of molecular sciences, 2021-12, Vol.22 (24), p.13452</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-7698e2bfcd33f3d5efdbec4efeef7c90c13a1213c1e41531e265999b3175076d3</citedby><cites>FETCH-LOGICAL-c415t-7698e2bfcd33f3d5efdbec4efeef7c90c13a1213c1e41531e265999b3175076d3</cites><orcidid>0000-0001-9058-8140</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704671/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704671/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34948249$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cui, Yanhua</creatorcontrib><creatorcontrib>Wang, Meihong</creatorcontrib><creatorcontrib>Zheng, Yankun</creatorcontrib><creatorcontrib>Miao, Kai</creatorcontrib><creatorcontrib>Qu, Xiaojun</creatorcontrib><title>The Carbohydrate Metabolism of Lactiplantibacillus plantarum</title><title>International journal of molecular sciences</title><addtitle>Int J Mol Sci</addtitle><description>has a strong carbohydrate utilization ability. This characteristic plays an important role in its gastrointestinal tract colonization and probiotic effects.
LP-F1 presents a high carbohydrate utilization capacity. The genome analysis of 165
strains indicated the species has a plenty of carbohydrate metabolism genes, presenting a strain specificity. Furthermore, two-component systems (TCSs) analysis revealed that the species has more TCSs than other lactic acid bacteria, and the distribution of TCS also shows the strain specificity. In order to clarify the sugar metabolism mechanism under different carbohydrate fermentation conditions, the expressions of 27 carbohydrate metabolism genes, catabolite control protein A (CcpA) gene
and TCSs genes were analyzed by quantitative real-time PCR technology. The correlation analysis between the expressions of regulatory genes and sugar metabolism genes showed that some regulatory genes were correlated with most of the sugar metabolism genes, suggesting that some TCSs might be involved in the regulation of sugar metabolism.</description><subject>Bacteria</subject><subject>Biosynthesis</subject><subject>Carbohydrate metabolism</subject><subject>Carbohydrate Metabolism - physiology</subject><subject>Carbohydrates</subject><subject>Chromosomes</subject><subject>Correlation analysis</subject><subject>Enzymes</subject><subject>Fermentation</subject><subject>Gastrointestinal system</subject><subject>Gastrointestinal tract</subject><subject>Genes</subject><subject>Genomes</subject><subject>Kinases</subject><subject>Lactic acid</subject><subject>Lactic acid bacteria</subject><subject>Lactiplantibacillus plantarum</subject><subject>Lactobacillaceae - metabolism</subject><subject>Lactobacillus - metabolism</subject><subject>Lactobacillus plantarum - metabolism</subject><subject>Lactose</subject><subject>Metabolism</subject><subject>Milk</subject><subject>Peptides</subject><subject>Phylogenetics</subject><subject>Prebiotics</subject><subject>Probiotics</subject><subject>Protein A</subject><subject>Protein turnover</subject><subject>Proteins</subject><subject>Signal transduction</subject><subject>Sugar</subject><issn>1422-0067</issn><issn>1661-6596</issn><issn>1422-0067</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkctLAzEQxoMotlaPXmXBi5fVvPYREEGKL6h4qeeQzU5sym5Tk12h_72prdJ6mhnmx8d88yF0TvA1YwLf2HkbKKWcMJ7RAzQknNIU47w43OkH6CSEOcaU0UwcowHjgpeUiyG6nc4gGStfudmq9qqD5BU6VbnGhjZxJpko3dlloxadrZS2TdOH5GdUvm9P0ZFRTYCzbR2h98eH6fg5nbw9vYzvJ6nmJOvSIhcl0MromjHD6gxMXYHmYABMoQXWhClCCdMEIs8I0DwTQlSMFBku8pqN0N1Gd9lXLdQaFp1XjVx62yq_kk5Zub9Z2Jn8cF-yLDDPCxIFrrYC3n32EDrZ2qChiUbA9UHSPL6KlVjwiF7-Q-eu94tob03RkuBM4EilG0p7F4IH83cMwXKdi9zLJfIXuw7-6N8g2DfFR4nS</recordid><startdate>20211215</startdate><enddate>20211215</enddate><creator>Cui, Yanhua</creator><creator>Wang, Meihong</creator><creator>Zheng, Yankun</creator><creator>Miao, Kai</creator><creator>Qu, Xiaojun</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-9058-8140</orcidid></search><sort><creationdate>20211215</creationdate><title>The Carbohydrate Metabolism of Lactiplantibacillus plantarum</title><author>Cui, Yanhua ; Wang, Meihong ; Zheng, Yankun ; Miao, Kai ; Qu, Xiaojun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-7698e2bfcd33f3d5efdbec4efeef7c90c13a1213c1e41531e265999b3175076d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Bacteria</topic><topic>Biosynthesis</topic><topic>Carbohydrate metabolism</topic><topic>Carbohydrate Metabolism - physiology</topic><topic>Carbohydrates</topic><topic>Chromosomes</topic><topic>Correlation analysis</topic><topic>Enzymes</topic><topic>Fermentation</topic><topic>Gastrointestinal system</topic><topic>Gastrointestinal tract</topic><topic>Genes</topic><topic>Genomes</topic><topic>Kinases</topic><topic>Lactic acid</topic><topic>Lactic acid bacteria</topic><topic>Lactiplantibacillus plantarum</topic><topic>Lactobacillaceae - metabolism</topic><topic>Lactobacillus - metabolism</topic><topic>Lactobacillus plantarum - metabolism</topic><topic>Lactose</topic><topic>Metabolism</topic><topic>Milk</topic><topic>Peptides</topic><topic>Phylogenetics</topic><topic>Prebiotics</topic><topic>Probiotics</topic><topic>Protein A</topic><topic>Protein turnover</topic><topic>Proteins</topic><topic>Signal transduction</topic><topic>Sugar</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cui, Yanhua</creatorcontrib><creatorcontrib>Wang, Meihong</creatorcontrib><creatorcontrib>Zheng, Yankun</creatorcontrib><creatorcontrib>Miao, Kai</creatorcontrib><creatorcontrib>Qu, Xiaojun</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of molecular sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cui, Yanhua</au><au>Wang, Meihong</au><au>Zheng, Yankun</au><au>Miao, Kai</au><au>Qu, Xiaojun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Carbohydrate Metabolism of Lactiplantibacillus plantarum</atitle><jtitle>International journal of molecular sciences</jtitle><addtitle>Int J Mol Sci</addtitle><date>2021-12-15</date><risdate>2021</risdate><volume>22</volume><issue>24</issue><spage>13452</spage><pages>13452-</pages><issn>1422-0067</issn><issn>1661-6596</issn><eissn>1422-0067</eissn><abstract>has a strong carbohydrate utilization ability. This characteristic plays an important role in its gastrointestinal tract colonization and probiotic effects.
LP-F1 presents a high carbohydrate utilization capacity. The genome analysis of 165
strains indicated the species has a plenty of carbohydrate metabolism genes, presenting a strain specificity. Furthermore, two-component systems (TCSs) analysis revealed that the species has more TCSs than other lactic acid bacteria, and the distribution of TCS also shows the strain specificity. In order to clarify the sugar metabolism mechanism under different carbohydrate fermentation conditions, the expressions of 27 carbohydrate metabolism genes, catabolite control protein A (CcpA) gene
and TCSs genes were analyzed by quantitative real-time PCR technology. The correlation analysis between the expressions of regulatory genes and sugar metabolism genes showed that some regulatory genes were correlated with most of the sugar metabolism genes, suggesting that some TCSs might be involved in the regulation of sugar metabolism.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>34948249</pmid><doi>10.3390/ijms222413452</doi><orcidid>https://orcid.org/0000-0001-9058-8140</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1422-0067 |
| ispartof | International journal of molecular sciences, 2021-12, Vol.22 (24), p.13452 |
| issn | 1422-0067 1661-6596 1422-0067 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8704671 |
| source | MDPI - Multidisciplinary Digital Publishing Institute; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Bacteria Biosynthesis Carbohydrate metabolism Carbohydrate Metabolism - physiology Carbohydrates Chromosomes Correlation analysis Enzymes Fermentation Gastrointestinal system Gastrointestinal tract Genes Genomes Kinases Lactic acid Lactic acid bacteria Lactiplantibacillus plantarum Lactobacillaceae - metabolism Lactobacillus - metabolism Lactobacillus plantarum - metabolism Lactose Metabolism Milk Peptides Phylogenetics Prebiotics Probiotics Protein A Protein turnover Proteins Signal transduction Sugar |
| title | The Carbohydrate Metabolism of Lactiplantibacillus plantarum |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T13%3A51%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Carbohydrate%20Metabolism%20of%20Lactiplantibacillus%20plantarum&rft.jtitle=International%20journal%20of%20molecular%20sciences&rft.au=Cui,%20Yanhua&rft.date=2021-12-15&rft.volume=22&rft.issue=24&rft.spage=13452&rft.pages=13452-&rft.issn=1422-0067&rft.eissn=1422-0067&rft_id=info:doi/10.3390/ijms222413452&rft_dat=%3Cproquest_pubme%3E2612810590%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2612810590&rft_id=info:pmid/34948249&rfr_iscdi=true |