Understanding CLL biology through mouse models of human genetics

Rapid advances in large-scale next-generation sequencing studies of human samples have progressively defined the highly heterogeneous genetic landscape of chronic lymphocytic leukemia (CLL). At the same time, the numerous challenges posed by the difficulties in rapid manipulation of primary B cells...

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Veröffentlicht in:	Blood 2021-12, Vol.138 (25), p.2621-2631
Hauptverfasser:	ten Hacken, Elisa, Wu, Catherine J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Gene Expression Regulation, Neoplastic Genomics Human Genetics Humans Leukemia, Lymphocytic, Chronic, B-Cell - genetics Mice Mice, Transgenic Mutation Neoplasm Transplantation Neoplasms, Experimental Review
Online-Zugang:	Volltext
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