Long Non-Coding RNAs at the Chromosomal Risk Loci Identified by Prostate and Breast Cancer GWAS

Long non-coding RNAs (lncRNAs) are emerging as key players in a variety of cellular processes. Deregulation of the lncRNAs has been implicated in prostate and breast cancers. Recently, germline genetic variations associated with cancer risk have been correlated with lncRNA expression and/or function...

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Veröffentlicht in:	Genes 2021-12, Vol.12 (12), p.2028
Hauptverfasser:	Janaththani, Panchadsaram, Srinivasan, Sri Lakshmi, Batra, Jyotsna
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Breast cancer Breast Neoplasms - genetics Cell growth Disease Female Gene expression Genetic diversity Genetic Predisposition to Disease Genomes Health risk assessment Humans Male Non-coding RNA Organ Specificity Prostate cancer Prostatic Neoplasms - genetics Proteins Review RNA polymerase RNA, Long Noncoding - genetics Single-nucleotide polymorphism Structure-function relationships Therapeutic targets
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