The Cap-Binding Complex CBC and the Eukaryotic Translation Factor eIF4E: Co-Conspirators in Cap-Dependent RNA Maturation and Translation

The translation of RNA into protein is a dynamic process which is heavily regulated during normal cell physiology and can be dysregulated in human malignancies. Its dysregulation can impact selected groups of RNAs, modifying protein levels independently of transcription. Integral to their suitabilit...

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Veröffentlicht in:	Cancers 2021-12, Vol.13 (24), p.6185
Hauptverfasser:	Mars, Jean-Clement, Ghram, Mehdi, Culjkovic-Kraljacic, Biljana, Borden, Katherine L B
Format:	Artikel
Sprache:	eng
Schlagworte:	Cytoplasm Enzymes Gene expression Initiation factor eIF-4E Integration Localization Malignancy Mammalian cells Mammals Metabolism Nuclear transport Phosphatase Polyadenylation Proteins Review RNA transport Transcription
Online-Zugang:	Volltext
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