Tissue-Nonspecific Alkaline Phosphatase, a Possible Mediator of Cell Maturation: Towards a New Paradigm

Alkaline phosphatase (ALP) is a ubiquitous membrane-bound glycoprotein capable of providing inorganic phosphate by catalyzing the hydrolysis of organic phosphate esters, or removing inorganic pyrophosphate that inhibits calcification. In humans, four forms of ALP cDNA have been cloned, among which t...

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Veröffentlicht in:	Cells (Basel, Switzerland) Switzerland), 2021-11, Vol.10 (12), p.3338, Article 3338
Hauptverfasser:	Sato, Masahiro, Saitoh, Issei, Kiyokawa, Yuki, Iwase, Yoko, Kubota, Naoko, Ibano, Natsumi, Noguchi, Hirofumi, Yamasaki, Youichi, Inada, Emi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Alkaline phosphatase Alkaline Phosphatase - metabolism Animals Bone marrow Calcification Cancer Cell Biology Cell Differentiation Coding Embryo cells Enzymes Esters Fatty acids Genetic disorders Humans Hypophosphatasia Inhibitory postsynaptic potentials Isoenzymes - metabolism juvenile cells Kidneys Life Sciences & Biomedicine Maturation Mesenchyme Models, Biological Mutation Neurogenesis Phosphatase Phosphate esters Pluripotency pluripotent stem cells Review Rodents Science & Technology signal regulator Signal Transduction somatic stem cells Stem cell transplantation Stem cells Teeth Thymus gland tissue-nonspecific alkaline phosphatase
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