Clinical significance and biological functions of chemokine CXCL3 in head and neck squamous cell carcinoma

CXCL3 plays extensive roles in tumorigenesis in various types of human cancers through its roles in tumor cell differentiation, invasion, and migration. However, the mechanisms of CXCL3 in head and neck squamous cell carcinoma (HNSCC) remain unclear. In our study, multiple databases were used to exp...

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Veröffentlicht in:	Bioscience reports 2021-12, Vol.41 (12), p.1
Hauptverfasser:	Guan, Jian, Weng, Jinru, Ren, Qiaosheng, Zhang, Chunbin, Hu, Liantao, Deng, Wenjun, Lu, Shizhen, Dong, Xinyu, Li, Weidong, Li, Yue, Wang, Weiqun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apoptosis BAX protein Bcl-2 protein Bioinformatics Cancer Cancer therapies Cell adhesion & migration Cell Cycle, Growth & Proliferation Cell differentiation Cell growth Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Cervical cancer Chemokines Chemokines, CXC - genetics Chemokines, CXC - metabolism Clinical significance Computational Biology Databases, Genetic Differentiation (biology) Extracellular signal-regulated kinase Female Gene expression Gene Expression Regulation, Neoplastic Genes Head & neck cancer Head and neck carcinoma Head and Neck Neoplasms - genetics Head and Neck Neoplasms - metabolism Head and Neck Neoplasms - pathology Humans In vivo methods and tests Kinases Lymphatic system Male MAP kinase Medical prognosis Metastasis Middle Aged Neck Neoplasm Invasiveness NF-κB protein Polymerase chain reaction Proteins Regression analysis Signal Transduction Squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck - genetics Squamous Cell Carcinoma of Head and Neck - metabolism Squamous Cell Carcinoma of Head and Neck - pathology Stat3 protein Survival Survival analysis Toll-like receptors Tumor cells Tumorigenesis Tumors
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