Exploiting differential effects of actomyosin contractility to control cell sorting among breast cancer cells

In order to gain a greater understanding of the factors that drive spatial organization in multicellular aggregates of cancer cells, we investigate the segregation patterns of 6 breast cell lines of varying degree of mesenchymal character during formation of mixed aggregates. Cell sorting is conside...

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Veröffentlicht in:	Molecular biology of the cell 2021-11, Vol.32 (21), p.ar24-ar24
Hauptverfasser:	Devanny, Alexander J, Vancura, Michelle B, Kaufman, Laura J
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - metabolism Actomyosin - metabolism Breast Neoplasms - metabolism Breast Neoplasms - physiopathology Cadherins - metabolism Cell Adhesion - physiology Cell Aggregation - physiology Cell Line, Tumor Cell Movement - drug effects Extracellular Matrix - metabolism Female Flow Cytometry - methods Humans Integrins - metabolism Spheroids, Cellular - metabolism
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