Interaction effect of serum serotonin level and age on the 12-week pharmacotherapeutic response in patients with depressive disorders

Despite the recognized antidepressant role of serotonin (5-hydroxytryptamine [5-HT]) signaling pathways in the central nervous system, the association between baseline peripheral 5-HT level and the antidepressant treatment response in clinical studies remains debatable. We investigated the interacti...

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Veröffentlicht in:	Scientific reports 2021-12, Vol.11 (1), p.24226-24226, Article 24226
Hauptverfasser:	Choi, Wonsuk, Kim, Ju-Wan, Kang, Hee-Ju, Kim, Hee Kyung, Kang, Ho-Cheol, Lee, Ju-Yeon, Kim, Sung-Wan, Stewart, Robert, Kim, Jae-Min
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308/409 692/53/2423 692/699/476/1414 Adolescent Adult Age Aged Aged, 80 and over Antidepressive Agents Central nervous system Depressive Disorder, Major - blood Depressive Disorder, Major - drug therapy Female Humanities and Social Sciences Humans Male Mental depression Mental disorders Middle Aged multidisciplinary Multidisciplinary Sciences Outpatients Patients Prospective Studies Psychiatric Status Rating Scales Regression analysis Remission Remission Induction Republic of Korea Science Science & Technology Science & Technology - Other Topics Science (multidisciplinary) Serotonin Serotonin - blood Serotonin - metabolism Serotonin Uptake Inhibitors - therapeutic use Signal Transduction Treatment Outcome Young Adult
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