Response kinetics of different classes of antibodies to SARS-CoV2 infection in the Japanese population: The IgA and IgG titers increased earlier than the IgM titers

•Serial antibody measurement is necessary to understand the immunity in COVID-19.•IgA was generated more rapidly against all the viral proteins than IgM and IgG.•The IgG responses to the S1 protein and RBD were maintained for a longer duration.•IgG or IgA seroconversion often preceded IgM seroconver...

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Veröffentlicht in:	International immunopharmacology 2022-02, Vol.103, p.108491-108491, Article 108491
Hauptverfasser:	Kurano, Makoto, Morita, Yoshifumi, Nakano, Yuki, Yokoyama, Rin, Shimura, Takuya, Qian, Chungen, Xia, Fuzhen, He, Fan, Zheng, Liang, Ohmiya, Hiroko, Kishi, Yoshiro, Okada, Jun, Yoshikawa, Naoyuki, Nakajima, Kazuki, Nagura, Yutaka, Okazaki, Hitoshi, Jubishi, Daisuke, Moriya, Kyoji, Seto, Yasuyuki, Yasui, Fumihiko, Kohara, Michinori, Wakui, Masatoshi, Kawamura, Takeshi, Kodama, Tatsuhiko, Yatomi, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibody Formation Antigens Asian People Coronaviruses COVID-19 COVID-19 - epidemiology COVID-19 - immunology Humans IgA IgG IgM Immune response Immunoglobulin A Immunoglobulin A - blood Immunoglobulin A - immunology Immunoglobulin G Immunoglobulin G - blood Immunoglobulin G - immunology Immunoglobulin M Immunoglobulin M - blood Immunoglobulin M - immunology Infections Japan - epidemiology Japan - ethnology Japanese population Kinetics Kinetics of antibody responses Nucleocapsid protein Nucleocapsids Populations Proteins Receptor-binding domain Respiratory diseases SARS-CoV-2 Seroconversion Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Spike protein Viral diseases Viral Proteins - immunology
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