Herpesviruses assimilate kinesin to produce motorized viral particles

Neurotropic alphaherpesviruses initiate infection in exposed mucosal tissues and, unlike most viruses, spread rapidly to sensory and autonomic nerves where life-long latency is established 1 . Recurrent infections arise sporadically from the peripheral nervous system throughout the life of the host,...

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Veröffentlicht in:	Nature (London) 2021-11, Vol.599 (7886), p.662-666
Hauptverfasser:	Pegg, Caitlin E., Zaichick, Sofia V., Bomba-Warczak, Ewa, Jovasevic, Vladimir, Kim, DongHo, Kharkwal, Himanshu, Wilson, Duncan W., Walsh, Derek, Sollars, Patricia J., Pickard, Gary E., Savas, Jeffrey N., Smith, Gregory A.
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/106 13/109 14 14/1 14/19 14/35 14/63 38 38/35 38/77 631/326/596/1553 631/326/596/2557 631/378/87 631/80/128/1923 631/80/304 82/29 82/80 Animals Autonomic nervous system Axons Biological Transport Capsid - metabolism Cell Line Cell Nucleus - virology Cellular structure Central nervous system Chlorocebus aethiops Critical components Development and progression Epithelial cells Epithelial Cells - metabolism Epithelial Cells - virology Epithelium Gene expression Health aspects Herpes Herpes simplex Herpes viruses Herpesvirus 1, Human - metabolism Herpesvirus 1, Suid - metabolism Herpesvirus diseases Herpesviruses Humanities and Social Sciences Humans Infections Invasiveness Kinesin Kinesins - metabolism Latency Localization Microtubules Motors Movement Mucosa multidisciplinary Nerves Nervous system Neurons - metabolism Neurons - virology Nuclei (cytology) Peripheral nervous system Physiological aspects Proteins Rabbits Science Science (multidisciplinary) Swine Virion - metabolism Virions Virus Assembly Viruses
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