HIV-1 Tat and cocaine impact astrocytic energy reservoir influence on miRNA epigenetic regulation

Astrocytes are the primary regulator of energy metabolism in the central nervous system (CNS), and impairment of astrocyte's energy resource may trigger neurodegeneration. HIV infections and cocaine use are known to alter epigenetic modification, including miRNAs, which can target gene expressi...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 2021-11, Vol.113 (6), p.3461-3475
Hauptverfasser:	Doke, Mayur, Kashanchi, Fatah, Khan, Mansoor A., Samikkannu, Thangavel
Format:	Artikel
Sprache:	eng
Schlagworte:	Astrocyte and cocaine Astrocytes - metabolism Cocaine - metabolism Cocaine - pharmacology Epigenesis, Genetic HIV Infections - genetics HIV Infections - metabolism HIV-1 - genetics HIV-1 Tat Humans MicroRNAs - genetics MicroRNAs - metabolism miRNA Piracetam
Online-Zugang:	Volltext
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