The design and synthesis of circular RNAs

•Diverse methodologies exist to produce circRNAs both in vitro and in vivo.•Methods for artificial circRNA synthesis in vivo resemble natural circRNA biogenesis.•Artificial circRNAs can be customized to carry out desired functions in cells. Circular RNAs (circRNAs) are a novel class of RNAs distingu...

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Bibliographische Detailangaben

Veröffentlicht in:	Methods (San Diego, Calif.) Calif.), 2021-12, Vol.196, p.85-103
Hauptverfasser:	Obi, Prisca, Chen, Y. Grace
Format:	Artikel
Sprache:	eng
Schlagworte:	Backsplicing CircRNA CircRNA minigene CircRNA translation In vitro transcription MicroRNAs - genetics MicroRNAs - metabolism Proteins - metabolism RNA Splicing - genetics RNA synthesis RNA, Circular
Online-Zugang:	Volltext
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