Increased Angiotensin-Converting Enzyme 2 and Loss of Alveolar Type II Cells in COVID-19–related Acute Respiratory Distress Syndrome

Rationale: ACE2 (angiotensin-converting enzyme 2), the entry receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is expressed in type 2 alveolar epithelial cells (AT2) that may play key roles in postinjury repair. An imbalance between ACE2 and ACE has also been hypothesized to...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2021-11, Vol.204 (9), p.1024-1034
Hauptverfasser:	Gerard, Ludovic, Lecocq, Marylene, Bouzin, Caroline, Hoton, Delphine, Schmit, Gregory, Pereira, Joao Pinto, Montiel, Virginie, Plante-Bordeneuve, Thomas, Laterre, Pierre-François, Pilette, Charles
Format:	Artikel
Sprache:	eng
Schlagworte:	Cells COVID-19 Enzymes Original Respiratory diseases Respiratory distress syndrome Studies
Online-Zugang:	Volltext
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