Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021

Corticosteroids are efficacious in treating chronic rhinosinusitis (CRS), but concerns on the potential side effects remain, especially for long-term usage of systemic corticosteroids. Accumulated evidence shows that transnasal nebulization may be a reasonable solution in balancing both efficacy and...

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Veröffentlicht in:Journal of thoracic disease 2021-11, Vol.13 (11), p.6217-6229
Hauptverfasser: Wang, Chengshuo, Cheng, Lei, Li, Huabin, Liu, Zheng, Lou, Hongfei, Shi, Jianbo, Sun, Ying, Wang, Dehui, Yang, Qintai, Yu, Hongmeng, Zhao, Changqing, Zhu, Dongdong, Cheng, Fengli, Li, Yan, Liao, Bo, Lu, Meiping, Meng, Cuida, Shen, Shen, Sun, Yueqi, Zheng, Rui, Zhang, Luo
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container_end_page 6229
container_issue 11
container_start_page 6217
container_title Journal of thoracic disease
container_volume 13
creator Wang, Chengshuo
Cheng, Lei
Li, Huabin
Liu, Zheng
Lou, Hongfei
Shi, Jianbo
Sun, Ying
Wang, Dehui
Yang, Qintai
Yu, Hongmeng
Zhao, Changqing
Zhu, Dongdong
Cheng, Fengli
Li, Yan
Liao, Bo
Lu, Meiping
Meng, Cuida
Shen, Shen
Sun, Yueqi
Zheng, Rui
Zhang, Luo
description Corticosteroids are efficacious in treating chronic rhinosinusitis (CRS), but concerns on the potential side effects remain, especially for long-term usage of systemic corticosteroids. Accumulated evidence shows that transnasal nebulization may be a reasonable solution in balancing both efficacy and safety. However, no consensus or guideline has been formulated on the use of steroid transnasal nebulization in treating CRS. The consensus is achieved through literature review and exchange of Chinese experts in Group of Otorhinolaryngology and Ophthalmology, Chinese Society of Allergy (CSA). This document covers the development, equipment, pharmacological mechanism, and evidence-based efficacy and safety, as well as the special concern of the application of steroid transnasal nebulization during the coronavirus disease (COVID-19) pandemic. The expert consensus clarifies the application of steroid transnasal nebulization in treating CRS and common comorbidities during the perioperative and postoperative periods.
doi_str_mv 10.21037/jtd-21-1142
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title Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021
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