Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021
Corticosteroids are efficacious in treating chronic rhinosinusitis (CRS), but concerns on the potential side effects remain, especially for long-term usage of systemic corticosteroids. Accumulated evidence shows that transnasal nebulization may be a reasonable solution in balancing both efficacy and...
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Veröffentlicht in: | Journal of thoracic disease 2021-11, Vol.13 (11), p.6217-6229 |
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container_title | Journal of thoracic disease |
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creator | Wang, Chengshuo Cheng, Lei Li, Huabin Liu, Zheng Lou, Hongfei Shi, Jianbo Sun, Ying Wang, Dehui Yang, Qintai Yu, Hongmeng Zhao, Changqing Zhu, Dongdong Cheng, Fengli Li, Yan Liao, Bo Lu, Meiping Meng, Cuida Shen, Shen Sun, Yueqi Zheng, Rui Zhang, Luo |
description | Corticosteroids are efficacious in treating chronic rhinosinusitis (CRS), but concerns on the potential side effects remain, especially for long-term usage of systemic corticosteroids. Accumulated evidence shows that transnasal nebulization may be a reasonable solution in balancing both efficacy and safety. However, no consensus or guideline has been formulated on the use of steroid transnasal nebulization in treating CRS. The consensus is achieved through literature review and exchange of Chinese experts in Group of Otorhinolaryngology and Ophthalmology, Chinese Society of Allergy (CSA). This document covers the development, equipment, pharmacological mechanism, and evidence-based efficacy and safety, as well as the special concern of the application of steroid transnasal nebulization during the coronavirus disease (COVID-19) pandemic. The expert consensus clarifies the application of steroid transnasal nebulization in treating CRS and common comorbidities during the perioperative and postoperative periods. |
doi_str_mv | 10.21037/jtd-21-1142 |
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Accumulated evidence shows that transnasal nebulization may be a reasonable solution in balancing both efficacy and safety. However, no consensus or guideline has been formulated on the use of steroid transnasal nebulization in treating CRS. The consensus is achieved through literature review and exchange of Chinese experts in Group of Otorhinolaryngology and Ophthalmology, Chinese Society of Allergy (CSA). This document covers the development, equipment, pharmacological mechanism, and evidence-based efficacy and safety, as well as the special concern of the application of steroid transnasal nebulization during the coronavirus disease (COVID-19) pandemic. The expert consensus clarifies the application of steroid transnasal nebulization in treating CRS and common comorbidities during the perioperative and postoperative periods.</description><identifier>ISSN: 2072-1439</identifier><identifier>EISSN: 2077-6624</identifier><identifier>DOI: 10.21037/jtd-21-1142</identifier><identifier>PMID: 34992802</identifier><language>eng</language><publisher>China: AME Publishing Company</publisher><subject>Consensus</subject><ispartof>Journal of thoracic disease, 2021-11, Vol.13 (11), p.6217-6229</ispartof><rights>2021 Journal of Thoracic Disease. All rights reserved.</rights><rights>2021 Journal of Thoracic Disease. All rights reserved. 2021 Journal of Thoracic Disease.</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662474/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662474/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34992802$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Chengshuo</creatorcontrib><creatorcontrib>Cheng, Lei</creatorcontrib><creatorcontrib>Li, Huabin</creatorcontrib><creatorcontrib>Liu, Zheng</creatorcontrib><creatorcontrib>Lou, Hongfei</creatorcontrib><creatorcontrib>Shi, Jianbo</creatorcontrib><creatorcontrib>Sun, Ying</creatorcontrib><creatorcontrib>Wang, Dehui</creatorcontrib><creatorcontrib>Yang, Qintai</creatorcontrib><creatorcontrib>Yu, Hongmeng</creatorcontrib><creatorcontrib>Zhao, Changqing</creatorcontrib><creatorcontrib>Zhu, Dongdong</creatorcontrib><creatorcontrib>Cheng, Fengli</creatorcontrib><creatorcontrib>Li, Yan</creatorcontrib><creatorcontrib>Liao, Bo</creatorcontrib><creatorcontrib>Lu, Meiping</creatorcontrib><creatorcontrib>Meng, Cuida</creatorcontrib><creatorcontrib>Shen, Shen</creatorcontrib><creatorcontrib>Sun, Yueqi</creatorcontrib><creatorcontrib>Zheng, Rui</creatorcontrib><creatorcontrib>Zhang, Luo</creatorcontrib><creatorcontrib>the Group of Otorhinolaryngology and Ophthalmology, Chinese Society of Allergy (CSA)</creatorcontrib><title>Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021</title><title>Journal of thoracic disease</title><addtitle>J Thorac Dis</addtitle><description>Corticosteroids are efficacious in treating chronic rhinosinusitis (CRS), but concerns on the potential side effects remain, especially for long-term usage of systemic corticosteroids. Accumulated evidence shows that transnasal nebulization may be a reasonable solution in balancing both efficacy and safety. However, no consensus or guideline has been formulated on the use of steroid transnasal nebulization in treating CRS. The consensus is achieved through literature review and exchange of Chinese experts in Group of Otorhinolaryngology and Ophthalmology, Chinese Society of Allergy (CSA). This document covers the development, equipment, pharmacological mechanism, and evidence-based efficacy and safety, as well as the special concern of the application of steroid transnasal nebulization during the coronavirus disease (COVID-19) pandemic. 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title | Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021 |
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