Elements of Th1/Th2 response and disease severity in COVID‐19 patients: A short report
The presence of a complex immune dysregulation syndrome has been established in COVID‐19 patients. We aimed to assess Th1/Th2 response in COVID‐19 patients and its association with disease severity by performing a prospective cohort study in a tertiary hospital COVID‐19 referral center. We report no...
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Veröffentlicht in: | Journal of medical virology 2022-01, Vol.94 (1), p.404-406 |
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container_title | Journal of medical virology |
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creator | Akinosoglou, Karolina Delastic, Anne‐Lise Dimakopoulou, Vasilina Marangos, Markos Gogos, Charalambos |
description | The presence of a complex immune dysregulation syndrome has been established in COVID‐19 patients. We aimed to assess Th1/Th2 response in COVID‐19 patients and its association with disease severity by performing a prospective cohort study in a tertiary hospital COVID‐19 referral center. We report no difference between Th1/Th2 responses between patients with severe and mild disease, except for levels of interleukin‐6 (IL‐6) and IL‐10. Future larger studies should examine lung‐specific versus systemic inflammatory responses, as well as, diverse immunotypes driving poor clinical outcomes. |
doi_str_mv | 10.1002/jmv.27313 |
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Future larger studies should examine lung‐specific versus systemic inflammatory responses, as well as, diverse immunotypes driving poor clinical outcomes.</description><subject>COVID-19</subject><subject>Inflammation</subject><subject>Interleukins</subject><subject>Lymphocytes T</subject><subject>Patients</subject><subject>SARS‐CoV‐2</subject><subject>Short Communication</subject><subject>Th1/Th2 response</subject><subject>Virology</subject><issn>0146-6615</issn><issn>1096-9071</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp1kc1u1DAUhS1ERYfCgjewxAYW6dzrv8YskKqhlFZF3QwVO8tJHMajJE7tzKDZ9RH6jDxJXaZCAonVvdL9ztG5OoS8QThGADZf99tjdsKRPyMzBK0KDSf4nMwAhSqUQnlIXqa0BoBSM_aCHHIhFCCTM_L9rHO9G6ZEQ0uXK5wvV4xGl8YwJEft0NDGJ2fzntzWRT_tqB_o4vrm4tOvu3vUdLSTf9R_oKc0rUKcsnrM4xU5aG2X3OuneUS-fT5bLr4UV9fnF4vTq6IWDHjBRC0FE1aWGrFyolZoVQOixFZDxa2FStlWVUJLUVpbNk0F1kktEKSVqPkR-bj3HTdV75o6Z4m2M2P0vY07E6w3f18GvzI_wtaUSjEAmQ3ePRnEcLtxaTK9T7XrOju4sEmGyQwqVBoy-vYfdB02ccjvZUorrjlKnqn3e6qOIaXo2j9hEMxjXyb3ZX73ldn5nv3pO7f7P2guv97sFQ8FaZTY</recordid><startdate>202201</startdate><enddate>202201</enddate><creator>Akinosoglou, Karolina</creator><creator>Delastic, Anne‐Lise</creator><creator>Dimakopoulou, Vasilina</creator><creator>Marangos, Markos</creator><creator>Gogos, Charalambos</creator><general>Wiley Subscription Services, Inc</general><general>John Wiley and Sons Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7TK</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7465-0784</orcidid><orcidid>https://orcid.org/0000-0002-4289-9494</orcidid></search><sort><creationdate>202201</creationdate><title>Elements of Th1/Th2 response and disease severity in COVID‐19 patients: A short report</title><author>Akinosoglou, Karolina ; Delastic, Anne‐Lise ; Dimakopoulou, Vasilina ; Marangos, Markos ; Gogos, Charalambos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4203-24c5424a58911be4c61a6d0481f90b3aa0b6af6b49548aa8ddb0ae594105a5193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>COVID-19</topic><topic>Inflammation</topic><topic>Interleukins</topic><topic>Lymphocytes T</topic><topic>Patients</topic><topic>SARS‐CoV‐2</topic><topic>Short Communication</topic><topic>Th1/Th2 response</topic><topic>Virology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Akinosoglou, Karolina</creatorcontrib><creatorcontrib>Delastic, Anne‐Lise</creatorcontrib><creatorcontrib>Dimakopoulou, Vasilina</creatorcontrib><creatorcontrib>Marangos, Markos</creatorcontrib><creatorcontrib>Gogos, Charalambos</creatorcontrib><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of medical virology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Akinosoglou, Karolina</au><au>Delastic, Anne‐Lise</au><au>Dimakopoulou, Vasilina</au><au>Marangos, Markos</au><au>Gogos, Charalambos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Elements of Th1/Th2 response and disease severity in COVID‐19 patients: A short report</atitle><jtitle>Journal of medical virology</jtitle><date>2022-01</date><risdate>2022</risdate><volume>94</volume><issue>1</issue><spage>404</spage><epage>406</epage><pages>404-406</pages><issn>0146-6615</issn><eissn>1096-9071</eissn><abstract>The presence of a complex immune dysregulation syndrome has been established in COVID‐19 patients. 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source | Wiley Journals |
subjects | COVID-19 Inflammation Interleukins Lymphocytes T Patients SARS‐CoV‐2 Short Communication Th1/Th2 response Virology |
title | Elements of Th1/Th2 response and disease severity in COVID‐19 patients: A short report |
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