Evolution of the SARS‐CoV‐2 proteome in three dimensions (3D) during the first 6 months of the COVID‐19 pandemic

Understanding the molecular evolution of the SARS‐CoV‐2 virus as it continues to spread in communities around the globe is important for mitigation and future pandemic preparedness. Three‐dimensional structures of SARS‐CoV‐2 proteins and those of other coronavirusess archived in the Protein Data Ban...

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Veröffentlicht in:	Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 2022-05, Vol.90 (5), p.1054-1080
Hauptverfasser:	Lubin, Joseph H., Zardecki, Christine, Dolan, Elliott M., Lu, Changpeng, Shen, Zhuofan, Dutta, Shuchismita, Westbrook, John D., Hudson, Brian P., Goodsell, David S., Williams, Jonathan K., Voigt, Maria, Sarma, Vidur, Xie, Lingjun, Venkatachalam, Thejasvi, Arnold, Steven, Alfaro Alvarado, Luz Helena, Catalfano, Kevin, Khan, Aaliyah, McCarthy, Erika, Staggers, Sophia, Tinsley, Brea, Trudeau, Alan, Singh, Jitendra, Whitmore, Lindsey, Zheng, Helen, Benedek, Matthew, Currier, Jenna, Dresel, Mark, Duvvuru, Ashish, Dyszel, Britney, Fingar, Emily, Hennen, Elizabeth M., Kirsch, Michael, Khan, Ali A., Labrie‐Cleary, Charlotte, Laporte, Stephanie, Lenkeit, Evan, Martin, Kailey, Orellana, Marilyn, Ortiz‐Alvarez de la Campa, Melanie, Paredes, Isaac, Wheeler, Baleigh, Rupert, Allison, Sam, Andrew, See, Katherine, Soto Zapata, Santiago, Craig, Paul A., Hall, Bonnie L., Jiang, Jennifer, Koeppe, Julia R., Mills, Stephen A., Pikaart, Michael J., Roberts, Rebecca, Bromberg, Yana, Hoyer, J. Steen, Duffy, Siobain, Tischfield, Jay, Ruiz, Francesc X., Arnold, Eddy, Baum, Jean, Sandberg, Jesse, Brannigan, Grace, Khare, Sagar D., Burley, Stephen K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid sequence Amino Acids Chemical properties coronavirus Coronaviruses COVID-19 Drug discovery Drug resistance Enzymatic activity Enzyme activity Evolution Humans Interfaces molecular Molecular evolution Normal distribution Nucleic acids Pandemics Prospective Studies protein Protein structure Proteins Proteome Proteomes Residues SARS-CoV-2 Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Spatial analysis Special issue: SARS‐CoV‐2 special issue for Proteins Structural proteins Viral diseases viral proteins Viral Proteins - genetics Viral Proteins - metabolism Virions Viruses
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