Terminal Ileitis as the Presenting Feature of Henoch-Schönlein Purpura in a 22-Year-Old Male
Henoch-Schönlein purpura (HSP) is a self-limited vasculitis that affects children and the preadolescent population. It is characterized by the deposition of immunoglobulin A immune complexes in tissues leading to palpable purpura, abdominal pain, arthritis, and nephropathy. When it occurs in adults,...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2021-11, Vol.13 (11), p.e19406 |
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| creator | Waleed, Muhammad Perinkulam Sathyanarayanan, Swaminathan Arif Maan, Soban Mansoor, Linta Hoerschgen, Kayla |
| description | Henoch-Schönlein purpura (HSP) is a self-limited vasculitis that affects children and the preadolescent population. It is characterized by the deposition of immunoglobulin A immune complexes in tissues leading to palpable purpura, abdominal pain, arthritis, and nephropathy. When it occurs in adults, the clinical manifestations are the same; however, adults present with more significant renal involvement. While abdominal pain is the most common gastrointestinal (GI) manifestation, it can also present with GI bleeding, intussusception, bowel ischemia, and bowel perforation. Here, we report the case of a 22-year-old gentleman who presented with nonspecific GI complaints such as nausea, vomiting, and loose stools. He was later found to have terminal ileitis preceding the onset of rash, the biopsy of which confirmed HSP. Terminal ileitis is a rare GI manifestation of HSP and is not very commonly reported in the literature. |
| doi_str_mv | 10.7759/cureus.19406 |
| format | Article |
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It is characterized by the deposition of immunoglobulin A immune complexes in tissues leading to palpable purpura, abdominal pain, arthritis, and nephropathy. When it occurs in adults, the clinical manifestations are the same; however, adults present with more significant renal involvement. While abdominal pain is the most common gastrointestinal (GI) manifestation, it can also present with GI bleeding, intussusception, bowel ischemia, and bowel perforation. Here, we report the case of a 22-year-old gentleman who presented with nonspecific GI complaints such as nausea, vomiting, and loose stools. He was later found to have terminal ileitis preceding the onset of rash, the biopsy of which confirmed HSP. Terminal ileitis is a rare GI manifestation of HSP and is not very commonly reported in the literature.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.19406</identifier><identifier>PMID: 34909326</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Abdomen ; Allergy/Immunology ; Arthritis ; Biopsy ; Case reports ; Chlamydia ; Colonoscopy ; Dermatology ; Diarrhea ; Edema ; Endoscopy ; Gastroenterology ; Inflammation ; Inflammatory bowel disease ; Neutrophils ; Pain ; Purpura ; Rheumatology ; Skin ; Small intestine ; Steroids</subject><ispartof>Curēus (Palo Alto, CA), 2021-11, Vol.13 (11), p.e19406</ispartof><rights>Copyright © 2021, Waleed et al.</rights><rights>Copyright © 2021, Waleed et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2021, Waleed et al. 2021 Waleed et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c266t-c31aea56a96cc736a61b36c26f2dfc1b3ba945e9e964c3cb28572f119dff5df43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658736/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658736/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34909326$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Waleed, Muhammad</creatorcontrib><creatorcontrib>Perinkulam Sathyanarayanan, Swaminathan</creatorcontrib><creatorcontrib>Arif Maan, Soban</creatorcontrib><creatorcontrib>Mansoor, Linta</creatorcontrib><creatorcontrib>Hoerschgen, Kayla</creatorcontrib><title>Terminal Ileitis as the Presenting Feature of Henoch-Schönlein Purpura in a 22-Year-Old Male</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Henoch-Schönlein purpura (HSP) is a self-limited vasculitis that affects children and the preadolescent population. 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Terminal ileitis is a rare GI manifestation of HSP and is not very commonly reported in the literature.</description><subject>Abdomen</subject><subject>Allergy/Immunology</subject><subject>Arthritis</subject><subject>Biopsy</subject><subject>Case reports</subject><subject>Chlamydia</subject><subject>Colonoscopy</subject><subject>Dermatology</subject><subject>Diarrhea</subject><subject>Edema</subject><subject>Endoscopy</subject><subject>Gastroenterology</subject><subject>Inflammation</subject><subject>Inflammatory bowel disease</subject><subject>Neutrophils</subject><subject>Pain</subject><subject>Purpura</subject><subject>Rheumatology</subject><subject>Skin</subject><subject>Small intestine</subject><subject>Steroids</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpVUcFKAzEUDKLYUnvzLAGvbk2yu9nNRZBibaHSgvXgQUKafWm3bHdrsiv4Y_6AP2Zqa6mnN_DmzQxvELqkpJcksbjVjYXG9aiICD9BbUZ5GqQ0jU6PcAt1nVsRQihJGEnIOWqFkSAiZLyN3mZg13mpCjwqIK9zh5XD9RLw1IKDss7LBR6Aqr0PrgweQlnpZfCsl99fpT8o8bSxm8Yq7KHCjAWvoGwwKTL8pAq4QGdGFQ66-9lBL4OHWX8YjCePo_79ONCM8zrQIVWgYq4E1zoJueJ0HnK_Mywz2uO5ElEMAgSPdKjnLI0TZigVmTFxZqKwg-52uptmvoZM--BWFXJj87Wyn7JSufy_KfOlXFQfMuVx6g29wPVewFbvDbharqrG-rc4yThjIiFcbG1udixtK-csmIMDJXLbh9z1IX_78PSr41QH8t_3wx92D4jK</recordid><startdate>20211109</startdate><enddate>20211109</enddate><creator>Waleed, Muhammad</creator><creator>Perinkulam Sathyanarayanan, Swaminathan</creator><creator>Arif Maan, Soban</creator><creator>Mansoor, Linta</creator><creator>Hoerschgen, Kayla</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PKEHL</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20211109</creationdate><title>Terminal Ileitis as the Presenting Feature of Henoch-Schönlein Purpura in a 22-Year-Old Male</title><author>Waleed, Muhammad ; 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| subjects | Abdomen Allergy/Immunology Arthritis Biopsy Case reports Chlamydia Colonoscopy Dermatology Diarrhea Edema Endoscopy Gastroenterology Inflammation Inflammatory bowel disease Neutrophils Pain Purpura Rheumatology Skin Small intestine Steroids |
| title | Terminal Ileitis as the Presenting Feature of Henoch-Schönlein Purpura in a 22-Year-Old Male |
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