Variability in Behavioral Phenotypes after Forced Swimming-Induced Stress in Rats Is Associated with Expression of the Glucocorticoid Receptor, Nurr1, and IL-1β in the Hippocampus

Individual differences in coping with stress may determine either a vulnerable or resilient phenotype. Therefore, it is important to better understand the biology underlying the behavioral phenotype. We assessed whether individual behavioral phenotype to acute stress is related with the hippocampal...

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Veröffentlicht in:	International journal of molecular sciences 2021-11, Vol.22 (23), p.12700
Hauptverfasser:	Ruiz-Sánchez, Elizabeth, López-Ramírez, Arely M, Ruiz-Chow, Ángel, Calvillo, Minerva, Reséndiz-Albor, Aldo A, Anguiano, Brenda, Rojas, Patricia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Psychological Animals Behavior Behavior, Animal - physiology Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - genetics Brain-Derived Neurotrophic Factor - metabolism Climbing Cytokines Disease Models, Animal Female Gene expression Genotype & phenotype Glucocorticoids Hippocampus Hippocampus - metabolism IL-1β Interleukin 1 Interleukin-1beta - genetics Interleukin-1beta - metabolism Male Mental disorders mRNA Nuclear Receptor Subfamily 4, Group A, Member 2 - genetics Nuclear Receptor Subfamily 4, Group A, Member 2 - metabolism Nuclear receptors Nurr1 protein Phenotype Phenotypes Phenotyping Protein synthesis Proteins Rats Rats, Wistar Receptors, Glucocorticoid - genetics Receptors, Glucocorticoid - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Stress Stress response Stress, Psychological Swimming
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