Distinct Adaptations of Mitochondrial Dynamics to Electrical Pulse Stimulation in Lean and Severely Obese Primary Myotubes

BACKGROUNDSkeletal muscle from lean and obese subjects elicit differential adaptations in response to exercise/muscle contractions. In order to determine whether obesity alters the adaptations in mitochondrial dynamics in response to exercise/muscle contractions and whether any of these distinct ada...

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Veröffentlicht in:	Medicine and science in sports and exercise 2021-06, Vol.53 (6), p.1151-1160
Hauptverfasser:	KUGLER, BENJAMIN A., DENG, WENQIAN, FRANCOIS, BERGOMI, ANDERSON, MEAGHAN, HINKLEY, J. MATTHEW, HOUMARD, JOSEPH A., GONA, PHILIMON N., ZOU, KAI
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Adult Cells, Cultured Dynamins - metabolism Electric Stimulation - methods Exercise - physiology Female GTP Phosphohydrolases - metabolism Humans Insulin - metabolism Mitochondrial Dynamics Mitochondrial Proteins - metabolism Mitophagy Muscle Contraction Muscle Fibers, Skeletal - physiology Obesity, Morbid - physiopathology Phosphorylation Signal Transduction Thinness - physiopathology
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