Development and Provisional Validation of a Multiplex LC-MRM-MS Test for Timely Kidney Injury Detection in Urine

Kidney injury is a complication frequently encountered in hospitalized patients. Early detection of kidney injury prior to loss of renal function is an unmet clinical need that should be targeted by a protein-based biomarker panel. In this study, we aim to quantitate urinary kidney injury biomarkers...

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Veröffentlicht in:	Journal of proteome research 2021-12, Vol.20 (12), p.5304-5314
Hauptverfasser:	van Duijl, Tirsa T, Ruhaak, L. Renee, Smit, Nico P. M, Pieterse, Mervin M, Romijn, Fred P. H. T. M, Dolezal, Natasja, Drijfhout, Jan Wouter, de Fijter, Johan W, Cobbaert, Christa M
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatography, Liquid - methods Humans Isotopes Kidney - chemistry Kidney - physiology Peptides - analysis Tandem Mass Spectrometry - methods
Online-Zugang:	Volltext
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