Three LHPP gene‐targeting co‐expressed microRNAs (microRNA‐765, microRNA‐21, and microRNA‐144) promote proliferation, epithelial‐mesenchymal transition, invasion, and are independent prognostic biomarkers in renal cell carcinomas patients

Background Renal cell carcinoma (RCC) is one of the highly malignant tumors in the world. Global Cancer Statistics 2020 estimated that there were 179,368 deaths from kidney tumors. Therefore, exploring the prognostic biomarkers of RCC is of great significance for RCC patients. This study aims to exp...

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Veröffentlicht in:	Journal of clinical laboratory analysis 2021-12, Vol.35 (12), p.e24077-n/a
Hauptverfasser:	Meng, Kexin, Li, Zongda, Cui, Xiaoying
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibodies Binding sites Biomarkers Biomarkers, Tumor - genetics Cancer Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - mortality Carcinoma, Renal Cell - pathology Cell Line, Tumor Cell proliferation Cell Proliferation - genetics Epithelial-Mesenchymal Transition - genetics Female Fibroblasts Fluorescence in situ hybridization Gene Expression Regulation, Neoplastic Humans Immunohistochemistry Inorganic Pyrophosphatase - genetics Inorganic Pyrophosphatase - metabolism Kidney cancer Kidney Neoplasms - genetics Kidney Neoplasms - mortality Kidney Neoplasms - pathology Localization Male Medical prognosis Medical research Mesenchyme MicroRNAs MicroRNAs - genetics Middle Aged miRNA Phosphohistidine phospholysine phosphohistidine inorganic pyrophosphate phosphatase Prognosis Proteins Renal cell carcinoma Reporter gene Survival Analysis Tumors Western blotting
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