Relevance of HLA gene polymorphisms in Romanian patients with chronic renal insufficiency undergoing renal transplantation

Background Chronic renal insufficiency (CRI) is a global public health problem with a high incidence in the Romanian population. In this study, we aimed to investigate genomic HLA polymorphisms in Romanian patients with CRI waiting for kidney transplantation. To determine the existence of a potentia...

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Veröffentlicht in:	Journal of clinical laboratory analysis 2021-12, Vol.35 (12), p.e24075-n/a
Hauptverfasser:	Mărunţelu, Ion, Cristea, Bogdan Mihai, Omer, Secil, Preda, Carmen Monica, Constantinescu, Ileana
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Case-Control Studies Child Child, Preschool combined HLA types CRI Disease disease‐associated HLA genes Drb1 protein Expected values Female Gene Frequency Gene polymorphism Genes Genotype & phenotype Haplotypes Health care Histocompatibility antigen HLA HLA Antigens - genetics Humans Kidney Transplantation Kidney transplants Male Middle Aged Polymerase chain reaction Polymorphism, Genetic polymorphisms Population Population studies Public health Renal insufficiency Renal Insufficiency, Chronic - genetics Renal Insufficiency, Chronic - therapy Romania Young Adult
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