Molecular mechanisms of sperm motility are conserved in an early-branching metazoan

Efficient and targeted sperm motility is essential for animal reproductive success. Sperm from mammals and echinoderms utilize a highly conserved signaling mechanism in which sperm motility is stimulated by pH-dependent activation of the cAMP-producing enzyme soluble adenylyl cyclase (sAC). However,...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2021-11, Vol.118 (48), p.1-9
Hauptverfasser:	Speer, Kelsey F., Allen-Waller, Luella, Novikov, Dana R., Barott, Katie L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylate cyclase Adenylyl Cyclases - metabolism Animal reproduction Animals Anthozoa - metabolism Anthozoa - physiology Biodiversity Biological Sciences Branching Breeding success Calcium - metabolism Calcium ions Climate change Corals Cyclic AMP Cyclic AMP - metabolism Cyclic AMP-Dependent Protein Kinases - metabolism Echinodermata Flagella Flagella - metabolism Homeostasis Homology Hydrogen-Ion Concentration Invertebrates Kinases Male Mammals Marine animals Marine invertebrates Marine organisms Mitochondria Molecular modelling Motility Na+/H+-exchanging ATPase pH effects pH sensors Phosphorylation Phylogeny Physiology Protein kinase A Proteins Reproduction Signal transduction Signaling Sperm Sperm Motility - physiology Spermatozoa - metabolism
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