COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions

The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global threat to human health and life. A useful pathological animal model accurately reflecting human pathology is needed to overcome the COVID-19 crisis. In the present study, COVID-19 cynomolgus monkey models includ...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2021-10, Vol.118 (43), p.1-9
Hauptverfasser:	Urano, Emiko, Okamura, Tomotaka, Ono, Chikako, Ueno, Shiori, Nagata, Satoshi, Kamada, Haruhiko, Higuchi, Mahoko, Furukawa, Mugi, Kamitani, Wataru, Matsuura, Yoshiharu, Kawaoka, Yoshihiro, Yasutomi, Yasuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral - blood Antibodies, Viral - immunology Biological Sciences COVID-19 - immunology COVID-19 - virology Disease Models, Animal Female Humans Immunoglobulin G - blood Immunoglobulin G - immunology Lung - diagnostic imaging Lung - immunology Lung - virology Macaca fascicularis - immunology Macaca fascicularis - virology Male Primate Diseases - immunology Primate Diseases - virology SARS-CoV-2 - immunology SARS-CoV-2 - physiology Tomography, X-Ray Computed - methods Virus Shedding - immunology Virus Shedding - physiology
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