Effects of zinc on tissue uptake and toxicity of lead in Sprague Dawley rat

Lead (Pb) exposure occurs together with other metals including zinc (Zn). This study investigated the impact of Zn on Pb tissue accumulation and Pb-induced toxicities. Animals (n=6 rats per group) were exposed to lead acetate (PbAc) or a combination of PbAc and zinc acetate (ZnAc) under the followin...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2021, Vol.83(11), pp.1674-1685
Hauptverfasser:	KATABA, Andrew, NAKAYAMA, Shouta M.M., YOHANNES, Yared Beyene, TOYOMAKI, Haruya, NAKATA, Hokuto, IKENAKA, Yoshinori, ISHIZUKA, Mayumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Body weight gain Catalase Enzymatic activity Enzymes Glutathione peroxidase Heavy metals Heme Heme oxygenase (decyclizing) Kidneys Lead mRNA Muscles oxidative stress Oxygenase Thioredoxin Toxicity Toxicology Zinc zinc co-administration
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