The spatiotemporal changes in dopamine, neuromelanin and iron characterizing Parkinson's disease

In Parkinson's disease, there is a progressive reduction in striatal dopaminergic function, and loss of neuromelanin-containing dopaminergic neurons and increased iron deposition in the substantia nigra. We tested the hypothesis of a relationship between impairment of the dopaminergic system an...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2021-11, Vol.144 (10), p.3114-3125
Hauptverfasser:	Biondetti, Emma, Santin, Mathieu D, Valabrègue, Romain, Mangone, Graziella, Gaurav, Rahul, Pyatigorskaya, Nadya, Hutchison, Matthew, Yahia-Cherif, Lydia, Villain, Nicolas, Habert, Marie-Odile, Arnulf, Isabelle, Leu-Semenescu, Smaranda, Dodet, Pauline, Vila, Miquel, Corvol, Jean-Christophe, Vidailhet, Marie, Lehéricy, Stéphane
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cohort Studies Corpus Striatum - diagnostic imaging Corpus Striatum - metabolism Dopamine - metabolism Female Humans Iron - metabolism Life Sciences Longitudinal Studies Magnetic Resonance Imaging - trends Male Melanins - metabolism Middle Aged Neurobiology Neurons and Cognition Original Parkinson Disease - diagnostic imaging Parkinson Disease - metabolism Prospective Studies Substantia Nigra - diagnostic imaging Substantia Nigra - metabolism Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!