FGD5‑AS1 is an oncogenic lncRNA in pancreatic cancer and regulates the Wnt/β‑catenin signaling pathway via miR‑577

The objective of the present study was to clarify the expression characteristics of long non‑coding RNA (lncRNA) FGD5 antisense RNA 1 (FGD5‑AS1) in pancreatic cancer, as well as its biological function and underlying mechanism. Reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) w...

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Veröffentlicht in:	Oncology reports 2022-01, Vol.47 (1), Article 21
Hauptverfasser:	Zhang, Wei-Tao, Zhang, Ji-Jun, Shao, Quan, Wang, Ying-Kai, Jia, Jie-Peng, Qian, Bo, Tian, Xiao-Wen, Yan, Wen-Ji
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged beta Catenin - genetics Binding sites Biotechnology Cell culture Down-Regulation Female Gene expression Guanine Nucleotide Exchange Factors - genetics Humans Kinases Male MicroRNAs MicroRNAs - genetics Middle Aged Oncogenes Pancreatic cancer Pancreatic Neoplasms - genetics Proteins RNA, Antisense - genetics RNA, Long Noncoding - genetics Up-Regulation Wnt Signaling Pathway Young Adult
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