Comparison of Whiskbroom and Pushbroom darkfield elastic light scattering spectroscopic imaging for head and neck cancer identification in a mouse model

The early detection of head and neck cancer is a prolonged challenging task. It requires a precise and accurate identification of tissue alterations as well as a distinct discrimination of cancerous from healthy tissue areas. A novel approach for this purpose uses microspectroscopic techniques with...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2021-12, Vol.413 (30), p.7363-7383
Hauptverfasser:	Bassler, Miriam C., Stefanakis, Mona, Sequeira, Inês, Ostertag, Edwin, Wagner, Alexandra, Bartsch, Jörg W., Roeßler, Marion, Mandic, Robert, Reddmann, Eike F., Lorenz, Anita, Rebner, Karsten, Brecht, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Animal models Animals Bayesian analysis Biochemistry Cancer Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Classification Comparative analysis Diagnosis Discriminant analysis Disease Models, Animal Elastic scattering Female Food Science Head & neck cancer Head and neck cancer Hyperspectral imaging Identification and classification Image resolution Laboratory Medicine Light Light scattering Male Mathematical models Medical imaging Methods Mice Mice, Inbred C57BL Monitoring/Environmental Analysis Paper in Forefront Principal Component Analysis Principal components analysis Reproducibility of Results Scanning devices Scattering, Radiation Spectral sensitivity Spectroscopy Spectrum analysis Squamous Cell Carcinoma of Head and Neck - diagnostic imaging Statistical analysis Statistical models Tissues Tongue Neoplasms - diagnostic imaging
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