Value of SERCA2a as a Biomarker for the Identification of Patients with Heart Failure Requiring Circulatory Support

Background: Heart failure (HF) alters the nucleo-cytoplasmic transport of cardiomyocytes and reduces SERCA2a levels, essential for intracellular calcium homeostasis. We consider in this study whether the molecules involved in these processes can differentiate those patients with advanced HF and the...

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Veröffentlicht in:	Journal of personalized medicine 2021-10, Vol.11 (11), p.1122
Hauptverfasser:	Ezzitouny, Meryem, Roselló-Lletí, Esther, Portolés, Manuel, Sánchez-Lázaro, Ignacio, Arnau-Vives, Miguel Ángel, Tarazón, Estefanía, Gil-Cayuela, Carolina, Lozano-Edo, Silvia, López-Vilella, Raquel, Almenar-Bonet, Luis, Martínez-Dolz, Luis
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Biobanks Biomarkers Ca2+-transporting ATPase Calcium (intracellular) Calcium (reticular) Calcium homeostasis Cardiomyocytes Congestive heart failure Enzymes Heart failure Heart transplantation Homeostasis Normal distribution Patients Plasma levels Precision medicine Sarcoplasmic reticulum Surgical apparatus & instruments Transplants & implants
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